THE RIGHT HON. SIR KINGSLEY WOOD,

Further consideration of the synthetic cannabinoids In July 2009 the Advisory Council on the Misuse of Drugs (ACMD) provided advice on harmful synthetic compounds (synthetic cannabinoid receptor agonists). These compounds had been identified in samples of smoking mixes such as „Spice ‟ and have a pharmacology similar to that of cannabis1. At the time, these previously unreported compounds were outside the control of the Misuse of Drugs Act (1971). It was concluded that these novel substances contained compounds with the potential for harm, similar to the harms of cannabis. Therefore, the ACMD recommended the compounds considered in that review should be made Class B and placed in Schedule I of the Misuse of Drugs Regulations (2001) under a generic definition. Given the wide range of compounds reported in the literature, the ACMD proposed five generic definitions for the synthetic cannabinoid agonists and five substances listed by name. The purpose of the generic definitions was to control similar compounds that would have associated harms that could be introduced at a later date. The cannabinoids targeted for control under these generic definitions were CB1 receptor agonists, identified by their ability to bind to this receptor. The CB1 receptor in the brain mediates the psychoactive effects of the principle active compounds in cannabis (Tetrahydrocannabinol (THC) and Cannabinol (CBN)). The ACMD‟s previous advice made clear that generic control for these compounds would likely require updating as those intent on producing such compounds find ways to circumvent the legislation.

The basic instrument of God on earth for witnessing and general service is the local church. This is His headquarters. Therefore, we must conclude that the key position for all Christian ser-vice on earth is the pastorate. There is a great need today to re-emphasize the place the local church and pastor occupy in God's total plan of redemption. Without the leadership of the pastor the work of the local church would suffer and no doubt ultimately die. Without the local church each other facet of Christian service ultimately would be impossible. For instance, the task of church extension could not be carried on. Where would we get the leadership, the men, and the money to establish new churches except from older, local churches? Foreign missions would be impossible for the same reason. Where would we secure the missionaries and the finances to support them in the fields of the world? There would certainly be no seminaries and Christian colleges if it were not for faithful pastors and local churches allover the world who support these necessary projects. This could be said of each facet of denomination-al work. Souls cannot be saved without soul-winners. Soul-winners are produced through teach-ing and training by pastors. This all demands the logic of Romans 10: 14: II How shall they hear without a preacher? II

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Memorandum by the Home Secretary.

capital and criminal justice in a

(HHS) on policy development issues, and is responsible for major activities in the areas of legislative and budget development, strategic planning, policy research and evaluation, and economic analysis. ASPE develops or reviews issues from the viewpoint of the Secretary, providing a perspective

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The Coalition for Evidence-Based Policy – a nonprofit, nonpartisan organization – strongly supports the Department’s proposed evidence criteria for the new HHS Home Visiting Program (Federal Register, July 23, 2010). Specifically, we believe the criteria in section 3.1 for rating the quality

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