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3,196
Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis
- J Clin Oncol
"... The expression of vascular endothelial growth factor (VEGF) by breast tumors has been previously correlated with a poor prognosis in the pathogenesis of breast cancer. Furthermore, VEGF secretion is a prerequisite for tumor development. Although most of the effects of VEGF have been shown to be attr ..."
Abstract
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Cited by 118 (0 self)
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to be attributable to the stimulation of endothelial cells, we present evidence here that breast tumor cells are capable of responding to VEGF. We show that VEGF stimulation of T-47D breast cancer cells leads to changes in cellular signaling and invasion. VEGF increases the cellular invasion of T-47D breast cancer
E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells
- J. Cell
, 1991
"... Abstract. The ability of carcinomas to invade and to metastasize largely depends on the degree of epithelial differentiation within the tumors, i.e., poorly differentiated being more invasive than well-differentiated carcinomas. Here we confirmed this correlation by examining various human cell line ..."
Abstract
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Cited by 114 (3 self)
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Abstract. The ability of carcinomas to invade and to metastasize largely depends on the degree of epithelial differentiation within the tumors, i.e., poorly differentiated being more invasive than well-differentiated carcinomas. Here we confirmed this correlation by examining various human cell
INVASIVE LOBULAR CARCINOMA OF THE BREAST by
"... The classical pattern of invasive lobular carcinoma (ILC) has become well established since the tumour was first designated in the 1940's. It is a distinct histological type of breast cancer, yet the incidence rates accumulated from the literature are widely divergent and vary from 0.7-20 per c ..."
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The classical pattern of invasive lobular carcinoma (ILC) has become well established since the tumour was first designated in the 1940's. It is a distinct histological type of breast cancer, yet the incidence rates accumulated from the literature are widely divergent and vary from 0.7-20 per
and early invasive breast carcinomas
"... Summary We have used polymerase chain reaction (PCR) analysis to study the incidence of allelic imbalance at four polymorphic microsatellite markers on chromosome 6q25.1-27, three dinucleotide repeats and one trinucleotide repeat, for microdissected tumour foci from a group of 75 'early ' ..."
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; breast carcinomas. The tumours comprised 16 preinvasive cases of ductal carcinoma in situ (DCIS) and 59 mammographically detected early invasive carcinomas. Loss of heterozygosity (LOH) was detected at all four loci and in all types and grade of disease. The frequency of LOH ranged from 23 % to 50
invasive breast cancer
"... Summary The intensity of angiogenesis as measured by the density of microvessels has been reported to be associated with a poor prognosis in invasive breast cancer in some, but not all, studies. The reasons for these discrepancies may be variations in the methodologies used. The monoclonal antibody ..."
Abstract
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Summary The intensity of angiogenesis as measured by the density of microvessels has been reported to be associated with a poor prognosis in invasive breast cancer in some, but not all, studies. The reasons for these discrepancies may be variations in the methodologies used. The monoclonal antibody
in invasive ductal carcinoma of breast
"... Background: Genomic alterations are important events in the origin and progression of various cancers, with DNA copy number changes associated with progression and treatment response in cancer. Array CGH is potentially useful in the identification of genomic alterations from primary tumor and blood ..."
Abstract
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in breast cancer patients. The aim of our study was to compare differences of DNA copy number changes in blood and tumor tissue in breast cancer. Methods: DNA copy number changes in blood were compared to those in tumor tissue using array-comparative genomic hybridization in samples obtained from 30 breast
measurements in invasive breast carcinoma∗
, 1997
"... The reproducibility of nuclear morphometric ..."
INVASIVE MICROPAPILLARY CARCINOMA OF THE BREAST: CASE
"... Invasive micropapillary carcinoma (IMPC) is a recently reported entity that is a histological variant of breast cancer with a poor prognosis. The tumor is best characterized by a nested pattern of eosinophilic tumor cells aranged in a solid, morular, tubular pattern. The tumor cells have intermediat ..."
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Invasive micropapillary carcinoma (IMPC) is a recently reported entity that is a histological variant of breast cancer with a poor prognosis. The tumor is best characterized by a nested pattern of eosinophilic tumor cells aranged in a solid, morular, tubular pattern. The tumor cells have
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