Results 1 - 10 of 58

Review The diagnosis and management of pre-invasive breast disease

by Radiological Diagnosis, Andy Evans , 2003
"... Pre-invasive disease is most frequently diagnosed in asymptomatic women following detection of microcalcification at mammography. The vast majority is ductal carcinoma in situ. This article summarizes the radiological features of pre-invasive disease and indicates which features are helpful in diffe ..."
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Pre-invasive disease is most frequently diagnosed in asymptomatic women following detection of microcalcification at mammography. The vast majority is ductal carcinoma in situ. This article summarizes the radiological features of pre-invasive disease and indicates which features are helpful

Review The diagnosis and management of pre-invasive breast disease Problems associated with management of pre-invasive lesions

by Anand D Purushotham , 2003
"... The treatment of ductal carcinoma in situ (DCIS) involves adequate surgical excision with adjuvant radiotherapy where appropriate. An inadequate excision margin and young age are independent risk factors for local recurrence. Routine surgery to axillary lymph nodes is not recommended in pure DCIS. I ..."
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to exclude coexisting DCIS or invasive disease.

Review The diagnosis and management of pre-invasive breast disease Genetic alterations in pre-invasive lesions

by Jorge S Reis-filho, Sunil R Lakhani , 2003
"... The development of modern molecular genetic techniques has allowed breast cancer researchers to clarify the multistep model of breast carcinogenesis. Laser capture microdissection coupled with comparative genomic hybridisation and/or loss-of-heterozygosity methods have confirmed that many pre-invasi ..."
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The development of modern molecular genetic techniques has allowed breast cancer researchers to clarify the multistep model of breast carcinogenesis. Laser capture microdissection coupled with comparative genomic hybridisation and/or loss-of-heterozygosity methods have confirmed that many pre-invasive

Molecular subtyping of DCIS: heterogeneity of breast cancer reflected in pre-invasive disease

by S E Clark , Jane Warwick , R Carpenter , R L Bowen , S W Duffy , J L Jones - Br J Cancer , 2011
"... BACKGROUND: Molecular profiling has identified at least four subtypes of invasive breast carcinoma, which exhibit distinct clinical behaviour. There is good evidence now that DCIS represents the non-obligate precursor to invasive breast cancer and therefore it should be possible to identify similar ..."
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. These subtypes were confirmed in an analysis on independent series of DCIS cases. CONCLUSION: This study indicates that DCIS may be classified in a similar manner to invasive breast cancer, and determining the relative frequency of different subtypes in DCIS and invasive disease may shed light on factors

Editorial The diagnosis and management of pre-invasive breast disease — current challenges, future hopes

by Sunil R Lakhani , 2003
"... The dogma of cancer biology is that tumours arise in a multistep fashion, and colon cancer has been the paradigm of this type of model. It is no surprise that the same model has been adopted in other cancer types, and breast ..."
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The dogma of cancer biology is that tumours arise in a multistep fashion, and colon cancer has been the paradigm of this type of model. It is no surprise that the same model has been adopted in other cancer types, and breast

Review The diagnosis and management of pre-invasive breast disease The role of new diagnostic techniques

by Ashutosh Nerurkar, Peter Osin , 2003
"... In recent years we have seen significantly increased use of minimally invasive diagnostic techniques in the management of breast disease. There is wide recognition of fine needle aspiration and core biopsy as the principal diagnostic methods. However, concerns exist regarding their reliability. This ..."
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In recent years we have seen significantly increased use of minimally invasive diagnostic techniques in the management of breast disease. There is wide recognition of fine needle aspiration and core biopsy as the principal diagnostic methods. However, concerns exist regarding their reliability

Pathological diagnosis – problems with existing classifications

by Marc J Van De Vijver, Hans Peterse , 2003
"... The diagnosis and management of pre-invasive breast disease ..."
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The diagnosis and management of pre-invasive breast disease

Letter

by Sunil R Lakhani , 2003
"... The diagnosis and management of pre-invasive breast disease: editor’s reply ..."
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The diagnosis and management of pre-invasive breast disease: editor’s reply

Letter

by Sunil Badve , 2003
"... The diagnosis and management of pre-invasive breast disease: another point of view ..."
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The diagnosis and management of pre-invasive breast disease: another point of view

Judicial review of

by Peter T Simpson, Theodora Gale, Laura G Fulford, Jorge S Reis-filho, Sunil R Lakhani - ACAS’, Industrial Law Journal , 1979
"... diagnosis and management of pre-invasive breast disease Pathology of atypical lobular hyperplasia and lobular carcinoma in situ ..."
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diagnosis and management of pre-invasive breast disease Pathology of atypical lobular hyperplasia and lobular carcinoma in situ
Results 1 - 10 of 58