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Viewpoints The Challenges of Mitochondrial Replacement
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BibTeX
@MISC{Chinnery_viewpointsthe,
author = {Patrick F. Chinnery and Lyndsey Craven and Shoukhrat Mitalipov and James B. Stewart and Mary Herbert and Douglass M. Turnbull},
title = {Viewpoints The Challenges of Mitochondrial Replacement},
year = {}
}
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Abstract
New advances in medicine often raise challenges, and none more so than those involving the manipulation of human oocytes and embryos. Issues around clin-ical need and ethical considerations must be taken into account, as well as the safety of the proposed technique. The discussion around the proposed mitochondrial re-placement techniques to prevent the transmission of mitochondrial DNA dis-ease has perhaps raised more challenges than most [1]. Mitochondrial DNA diseases are both common and, in their severest forms, devastating [2]. There are limited treat-
