Tools
Sorted by:
Try your query at:
 |
 |
 |
 |
 |
 |
Results 1 - 10
of
38,612
Apoptosis: a Basic Biological Phenomenon with Wide-ranging Implications in Tissue Kinetics
- Br. J. Cancer
, 1972
"... Summary.-The term apoptosis is proposed for a hitherto little recognized mechanism of controlled cell deletion, which appears to play a complementary but opposite role to mitosis in the regulation of animal cell populations. Its morphological features suggest that it is an active, inherently program ..."
Abstract
-
Cited by 641 (6 self)
- Add to MetaCart
Summary.-The term apoptosis is proposed for a hitherto little recognized mechanism of controlled cell deletion, which appears to play a complementary but opposite role to mitosis in the regulation of animal cell populations. Its morphological features suggest that it is an active, inherently
Rho GTPases and the actin cytoskeleton
- Science
, 1998
"... The actin cytoskeleton mediates a variety of essential biological functions in all eukaryotic cells. In addition to providing a structural framework around which cell shape and polarity are defined, its dynamic properties provide the driving force for cells to move and to divide. Understanding the b ..."
Abstract
-
Cited by 615 (4 self)
- Add to MetaCart
The actin cytoskeleton mediates a variety of essential biological functions in all eukaryotic cells. In addition to providing a structural framework around which cell shape and polarity are defined, its dynamic properties provide the driving force for cells to move and to divide. Understanding
The serial cultivation of human diploid cell strains. Exp Cell Res
, 1961
"... ONLY limited success has been obtained in developing strains of human cells that can be cultivated for long periods of time in vitro and that still preserve the diploid chromosomal configuration [41, 47, 48, 58, 591. Indeed, heteroploidy may be a necessary corollary or even the cause of the altera-t ..."
Abstract
-
Cited by 497 (2 self)
- Add to MetaCart
hundred have been reported in the literature, have serious limitations for many kinds of biological studies. Chief among these is the exclusion of their use for the production of human virus vaccines. This limitation is based on the supposition that such hetero-ploid cell lines, whether of normal
From genomics to chemical genomics: new developments in KEGG
- Nucleic Acids Res
, 2006
"... The increasing amount of genomic and molecular information is the basis for understanding higherorder biological systems, such as the cell and the 15 organism, and their interactions with the environment, as well as for medical, industrial and other practical applications. The KEGG resource ..."
Abstract
-
Cited by 529 (30 self)
- Add to MetaCart
The increasing amount of genomic and molecular information is the basis for understanding higherorder biological systems, such as the cell and the 15 organism, and their interactions with the environment, as well as for medical, industrial and other practical applications. The KEGG resource
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
- J. Cell
, 1992
"... Abstract. Programmed cell death (PCD) plays a key role in developmental biology and in maintenance of the steady state in continuously renewing tissues. Currently, its existence is inferred mainly from gel electrophoresis of a pooled DNA extract as PCD was shown to be associated with DNA fragmentati ..."
Abstract
-
Cited by 691 (0 self)
- Add to MetaCart
Abstract. Programmed cell death (PCD) plays a key role in developmental biology and in maintenance of the steady state in continuously renewing tissues. Currently, its existence is inferred mainly from gel electrophoresis of a pooled DNA extract as PCD was shown to be associated with DNA
Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics
- Mol. Cell. Proteomics
, 2002
"... The abbreviations used are: SILAC: Stable isotope labeling by amino acids in cell culture, 2DE: two dimensional (isoelectric focusing/SDS-PAGE) gel electrophoresis: ICATTM: isotope-coded affinity tag; MS: mass spectrometry; MALDI-TOF: matrix assisted laser desorption ionization-time of flight; PMF: ..."
Abstract
-
Cited by 595 (23 self)
- Add to MetaCart
The abbreviations used are: SILAC: Stable isotope labeling by amino acids in cell culture, 2DE: two dimensional (isoelectric focusing/SDS-PAGE) gel electrophoresis: ICATTM: isotope-coded affinity tag; MS: mass spectrometry; MALDI-TOF: matrix assisted laser desorption ionization-time of flight; PMF
Using Bayesian networks to analyze expression data
- Journal of Computational Biology
, 2000
"... DNA hybridization arrays simultaneously measure the expression level for thousands of genes. These measurements provide a “snapshot ” of transcription levels within the cell. A major challenge in computational biology is to uncover, from such measurements, gene/protein interactions and key biologica ..."
Abstract
-
Cited by 1088 (17 self)
- Add to MetaCart
DNA hybridization arrays simultaneously measure the expression level for thousands of genes. These measurements provide a “snapshot ” of transcription levels within the cell. A major challenge in computational biology is to uncover, from such measurements, gene/protein interactions and key
The Large-Scale Organization of Metabolic Networks
, 2000
"... In a cell or microorganism the processes that generate mass, energy, information transfer, and cell fate specification are seamlessly integrated through a complex network of various cellular constituents and reactions. However, despite the key role these networks play in sustaining various cellular ..."
Abstract
-
Cited by 609 (7 self)
- Add to MetaCart
In a cell or microorganism the processes that generate mass, energy, information transfer, and cell fate specification are seamlessly integrated through a complex network of various cellular constituents and reactions. However, despite the key role these networks play in sustaining various cellular
Hierarchical Models of Object Recognition in Cortex
, 1999
"... The classical model of visual processing in cortex is a hierarchy of increasingly sophisticated representations, extending in a natural way the model of simple to complex cells of Hubel and Wiesel. Somewhat surprisingly, little quantitative modeling has been done in the last 15 years to explore th ..."
Abstract
-
Cited by 836 (84 self)
- Add to MetaCart
The classical model of visual processing in cortex is a hierarchy of increasingly sophisticated representations, extending in a natural way the model of simple to complex cells of Hubel and Wiesel. Somewhat surprisingly, little quantitative modeling has been done in the last 15 years to explore
The Advantages of Evolutionary Computation
, 1997
"... Evolutionary computation is becoming common in the solution of difficult, realworld problems in industry, medicine, and defense. This paper reviews some of the practical advantages to using evolutionary algorithms as compared with classic methods of optimization or artificial intelligence. Specific ..."
Abstract
-
Cited by 541 (6 self)
- Add to MetaCart
and optimization mechanism. Evolved biota demonstrate optimized complex behavior at every level: the cell, the organ, the individual, and the population. The problems that biological species have solved are typified by chaos, chance, temporality, and nonlinear interactivities. These are also characteristics
Results 1 - 10
of
38,612
