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143
The Redox-Sensitive Transcriptional Activator OxyR Regulates the Peroxide Response Regulon in the Obligate
, 2000
"... Updated information and services can be found at: ..."
Mutational analysis of the redox-sensitive transcriptional regulator OxyR: regions important for oxidation and transcriptional activation
- J. Bacteriol. 177:1275
, 1995
"... Mutational analysis of the redox-sensitive ..."
Mutational Analysis To Define an Activating Region on the Redox-Sensitive Transcriptional Regulator OxyR �
, 2006
"... These include: This article cites 23 articles, 10 of which can be accessed free at: ..."
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These include: This article cites 23 articles, 10 of which can be accessed free at:
Regulator OxyR: Regions Important for Oxidation and Transcriptional Activation
, 1994
"... G. Mutational analysis of the redox-sensitive transcriptional regulator OxyR: regions important for oxidation and transcriptio... ..."
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G. Mutational analysis of the redox-sensitive transcriptional regulator OxyR: regions important for oxidation and transcriptio...
Redox-sensitive mechanisms of phytochemicalmediated inhibition of cancer cell proliferation,”The
- Journal of Nutritional Biochemistry
, 2003
"... ***Reprinted with permission. No further reproduction is authorized without written permission from Elsevier. This version of the document is not the version of record. Figures and/or pictures may be missing from this format of the document.*** Phytochemicals are potential cancer chemopreventive age ..."
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Cited by 14 (0 self)
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to constantly activate redox-sensitive transcription factors and responsive genes that are involved in the survival of cancer cells as well as their proliferation. With such a reliance of cancer cells on H2O2, it follows that if the excess H2O2 can be scavenged by phenolic phytochemicals having antioxidant
A cluster of constitutive mutations affecting the C-terminus of the redox-sensitive SoxR transcriptional activator. Nucleic Acids Res
, 1994
"... Activation of Escherichia coli oxidative stress regulon genes (sodA, zwf, fumC, nfo, etc.) is mediated by a two-stage regulatory system: the redox-sensitive SoxR protein transcriptionally activates the soxS gene, whose product then stimulates transcription of the regulon genes. Previous experiments ..."
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Cited by 6 (3 self)
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Activation of Escherichia coli oxidative stress regulon genes (sodA, zwf, fumC, nfo, etc.) is mediated by a two-stage regulatory system: the redox-sensitive SoxR protein transcriptionally activates the soxS gene, whose product then stimulates transcription of the regulon genes. Previous experiments
Role of oxyR in the oral anaerobe Porphyromonas gingivalis
- J. Bacteriol. 188:2454–2462. TABLE
, 2006
"... Porphyromonas gingivalis is an anaerobic microorganism that inhabits the oral cavity, where oxidative stress represents a constant challenge. A putative transcriptional regulator associated with oxidative stress, an oxyR homologue, is known from the P. gingivalis W83 genome sequence. We used microa ..."
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Cited by 7 (1 self)
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. In conclusion, these results suggest that OxyR does not act as a sensor of H 2 O 2 in P. gingivalis but constitutively activates transcription of oxidative-stress-related genes under anaerobic growth.
Redox-sensitive tRanscRiption factoRs eGR-1 and sp1 in the pathoGenesis of expeRimental GastRic ulceR
, 2015
"... Changes in redox status of gastric mucosa cells are the main pathogenic factor of gastric erosion and gastric ulcer development. Pro-oxidants can affect cell transcription activity via changes in redox- G astric ulcer is one of the most widespread pathologies of gastrointestinal tract. Moreover, it ..."
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, it has a tendency to increase in occurrence Egr-1 (Early growth response protein 1) is a redox-sensitive transcription factor (also called Krox-24, NGFI-A, zif268). It is an early response protein because various factors, including hypoxia, growth factors, interleukins, hormones, and neurotransmitters
Characterization of OxyR as a Negative Transcriptional Regulator That Represses Catalase Production in
"... Corynebacterium diphtheriae and Corynebacterium glutamicum each have one gene (cat) encoding catalase. In-frame Dcat mutants of C. diphtheriae and C. glutamicum were hyper-sensitive to growth inhibition and killing by H2O2. InC. diphtheriae C7(b), both catalase activity and cat transcription decreas ..."
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Corynebacterium diphtheriae and Corynebacterium glutamicum each have one gene (cat) encoding catalase. In-frame Dcat mutants of C. diphtheriae and C. glutamicum were hyper-sensitive to growth inhibition and killing by H2O2. InC. diphtheriae C7(b), both catalase activity and cat transcription
Escherichia coli OxyR protein represses the unmethylated bacteriophage Mu mom operon without blocking binding of the transcriptional activator
- C. Nucleic Acids
, 1996
"... Transcription of the bacteriophage Mu mom operon requires transactivation by the phage-encoded C protein. DNase I footprinting showed that in the absence of C, Escherichia coli RNA polymerase Eσ70 (RNAP) binds to the mom promoter (Pmom) region at a site, P2(from –64 to –11 with respect to the transc ..."
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is required to prevent binding of the E.coli OxyR protein, which represses mom transcription in dam – strains. OxyR, known to induce DNA bending, is normally in a reduced conformation in vivo, but is
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143
