prognostic evaluation in type 2 diabetic patients with angiographically normal coronary arteries.

CT volume measurement for prognostic evaluation of unresectable hepatocellular carcinoma after TACE

index in prognostic evaluation of patients with moderately differentiated hepatocellular carcinoma

G-protein–coupled receptors (GPCRs) are a superfamilyof more than 1000 membrane proteins that respond to a wide spectrum of extracellular signals, modulating various physiopathological processes.1,2 Several GPCRs, such as adrenergic, angiotensin, endothelin, and adenosine receptors, are expressed in cardiovascular (CV) tissues to maintain CV homeostasis. Importantly, GPCR-mediated adrenergic dereg-ulation has been shown to both cause and contribute to the onset and progression of major CV diseases ultimately leading to heart failure (HF). Thus, GPCRs have become salient targets of current pharmacotherapy in CV disorders, and in past decades, many efforts have been made to better clarify their role in the pathophysiology of cardiac disease, focusing not only on receptor functions but also on postre-ceptor components that mediate or regulate their responses. Among the latter, a relevant role has been attributed to G-protein–coupled receptor kinases (GRKs). In this review, we focus on GRK2, the most abundant and versatile GRK expressed on CV system, tracing the way from initial exper-imental evidence to more recent data suggesting a potential role for this kinase in the clinical management of HF.1,2

a stringent performance evaluation so that the significance of the concept can be fully exploited. Currently, prognostics concepts lack standard definitions and suffer from ambiguous and inconsistent interpretations. This lack of standards is in part due to the varied end-user requirements

Mid-regional pro-atrial natriuretic peptide and pro-adrenomedullin testing for the diagnostic and prognostic evaluation of patients with acute dyspnoea

The use of ambulatory monitoring in the prognostic evaluation of patients with sustained ventricular tachycardia treated with amiodarone

A novel approach to diagnostic and prognostic evaluations applied to railways: A real case study

ISSN 0948-0382 © IOS Press. All rights reserved The prognostic evaluation of tumor angiogenesis in invasive breast carcinoma*

IOS Press Non-invasive diagnostic and prognostic evaluation of liver cirrhosis and portal hypertension