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Interaction With ACE Gene I Allele

by Angiotensinogen Gene Haplotype, Chia-ti Tsai, Daniele Fallin, Fu-tien Chiang, Juey-jen Hwang, Ling-ping Lai, Kuan-lih Hsu, Chuen-den Tseng, Chiau-suong Liau, Yung-zu Tseng
"... Abstract—There are many reports demonstrating the association of renin-angiotensin system gene polymorphisms with hypertension in different populations. In the present study, we used haplotype analyses of the angiotensinogen gene with a new permutation-based hypothesis testing method to determine th ..."
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Abstract—There are many reports demonstrating the association of renin-angiotensin system gene polymorphisms with hypertension in different populations. In the present study, we used haplotype analyses of the angiotensinogen gene with a new permutation-based hypothesis testing method to determine

Haplotype structure of five SNPs within the ACE gene in the Tunisian population

by Maha Rebaï , Najla Kharrat , Imen Ayadi , Ahmed Rebaï
"... Abstract Background: The Angiotensin-Converting Enzyme (ACE) is a candidate gene in the aetiology of several common diseases. The study of the haplotype structure of this gene is of interest in diagnosis and in pharmacogenomics. Aim: The study investigated the haplotype profile of single nucleotide ..."
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Abstract Background: The Angiotensin-Converting Enzyme (ACE) is a candidate gene in the aetiology of several common diseases. The study of the haplotype structure of this gene is of interest in diagnosis and in pharmacogenomics. Aim: The study investigated the haplotype profile of single

Converting Enzyme (ACE) Gene Increase the Susceptibility to Hypertension and / or Diabetes

by B. A. Bhavani, T. Padma, B. K. S. Sastry, N. Krishna Reddy, K. Nausheen
"... ABSTRACT The causes of hypertension and type II diabetes (NIDDM) are mainly unknown, but they arise from interplay between several genetic and environmental factors. Hence the present study was aimed to investigate whether the Insertion I / Deletion D polymorphism of angiotensin-converting enzyme (A ..."
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(ACE) gene increase the susceptibility to hypertension and / or diabetes. ACE gene was genotyped in 200 hypertension patients, 100 type II diabetic patients and 200 age and sex matched controls. From the present data it was observed that in hypertension patients genotypic and allelic frequencies were

Insertion-Deletion Polymorphism of the ACE Gene Modulates

by Arshed A. Quyyumi, Abhiram Prasad, Suresh Narayanan, Syed Husain, Feroz Padder, Myron Waclawiw
"... The online version of this article, along with updated information and services, is located on the ..."
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The online version of this article, along with updated information and services, is located on the

POLYMORPHISM OF THE ACE GENE AND THE α-ACTININ-3 GENE IN ADOLESCENT IDIOPATHIC SCOLIOSIS

by Departmentof Orthopedics, Federal São, São Paulo
"... Objective: The I/D polymorphism of angiotensin-converting en-zyme (ACE) and R577X of the α-actinin-3 (ACTN3) is related to changes in skeletal muscle function. The aim of this study was to evaluate the distribution of these polymorphisms in a family with multiple members with adolescent idiopathic s ..."
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sco-liosis (AIS). Methods: Evaluated 25 subjects from a family with multiple members with AIS, by collecting 10mL of blood for DNA isolation. The genotyping of the I/D polymorphism of the ACE gene and the R577X of the ACTN3 gene was performed using two specific primers to classify individuals

DNA Methylation Analysis of the Angiotensin Converting Enzyme (ACE) Gene in Major Depression

by Peter Zill, Thomas C. Baghai, Christoph Born, Wolfgang Eisenmenger, Gabriella Varallo-bedarida, Brigitta Bondy
"... Background: The angiotensin converting enzyme (ACE) has been repeatedly discussed as susceptibility factor for major depression (MD) and the bi-directional relation between MD and cardiovascular disorders (CVD). In this context, functional polymorphisms of the ACE gene have been linked to depression ..."
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Background: The angiotensin converting enzyme (ACE) has been repeatedly discussed as susceptibility factor for major depression (MD) and the bi-directional relation between MD and cardiovascular disorders (CVD). In this context, functional polymorphisms of the ACE gene have been linked

Association of Angiotensin Converting Enzyme (ACE) Gene Polymorphism and Diabetic Nephropathy

by T Golmohamadi, A Nikzamir, M Nakhjavani, M Zahrai, A Amirzargar, R Saffari , 2006
"... Angiotensin I-converting Enzyme (ACE) gene polymorphism; genotype DD or D allele may be involved with an increased susceptibility to type 2 diabetes and diabetic nephropathy (DN). We examined the frequency of ACE gene polymorphism in 170 patients (85 type 2 diabetes with nephropathy and 85 without i ..."
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Angiotensin I-converting Enzyme (ACE) gene polymorphism; genotype DD or D allele may be involved with an increased susceptibility to type 2 diabetes and diabetic nephropathy (DN). We examined the frequency of ACE gene polymorphism in 170 patients (85 type 2 diabetes with nephropathy and 85 without

Regulation of ACE gene expression and plasma levels during rat postnatal development

by Olivier Costerousse, Jacqueline Allegrini, Huaming Huang, Jacob Bounhik, Francois Alhenc-gelas, Costerousse Olivier Jacqueline Allegrini, Jacob Bounhik, Frangois Alhenc-gelas - Am. J. Physiol , 1994
"... Regulation of ACE gene expression and plasma levels during rat postnatal development. Am. J. Physiol. 267 (Endocrinol. Metab. 30): E745-E753, 1994.-Angiotensin I-converting en-zyme (kininase II, ACE) is a transmembrane ectoenzyme of vascular endothelial cells that is also secreted in plasma. To unde ..."
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Regulation of ACE gene expression and plasma levels during rat postnatal development. Am. J. Physiol. 267 (Endocrinol. Metab. 30): E745-E753, 1994.-Angiotensin I-converting en-zyme (kininase II, ACE) is a transmembrane ectoenzyme of vascular endothelial cells that is also secreted in plasma

ACE gene insertion/deletion polymorphism modulates capillary permeability in hypertension

by Giulia Dell'omo , Giuseppe Penno , Laura Pucci , Daniela Lucchesi , Carmen Fotino , Stefano Del Prato , Roberto Pedrinelli , 2006
"... A B S T R A C T A D/D (deletion/deletion) polymorphism within the ACE (angiotensin 1-converting enzyme) gene increases the risk of microalbuminuria, a predictor of atherosclerotic vascular disease, in essential hypertension. It is unknown, however, whether this genetic profile is accompanied by dis ..."
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A B S T R A C T A D/D (deletion/deletion) polymorphism within the ACE (angiotensin 1-converting enzyme) gene increases the risk of microalbuminuria, a predictor of atherosclerotic vascular disease, in essential hypertension. It is unknown, however, whether this genetic profile is accompanied

Brief Genetics Report Insertion/Deletion Polymorphism of the ACE Gene Is Associated With Type

by Guoying Wang, Xiping Xu
"... In an attempt to examine the role of an ACE gene insertion/deletion (I/D) polymorphism in type 2 diabe-tes, we conducted a case-control association study among 132 couple-pairs from northern China. The geno-type frequencies for II, ID, and DD were 39.8, 39.8, and 20.3%, respectively, in the case gro ..."
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In an attempt to examine the role of an ACE gene insertion/deletion (I/D) polymorphism in type 2 diabe-tes, we conducted a case-control association study among 132 couple-pairs from northern China. The geno-type frequencies for II, ID, and DD were 39.8, 39.8, and 20.3%, respectively, in the case
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