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RESEARCH Decreased P27 protein ex h
"... carcinoma derived from mucosal epithelium of the naso- genes among NPC and nasopharyngeal tissues (NP) and ..."
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carcinoma derived from mucosal epithelium of the naso- genes among NPC and nasopharyngeal tissues (NP) and
ex
"... Proteomic analysis of Lawsonia intracellularis reveals expression of outer membrane proteins during infection ..."
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Proteomic analysis of Lawsonia intracellularis reveals expression of outer membrane proteins during infection
Ex
"... The uncoupling protein (UCP) is an integral protein of the tissue specific. UCP1 has a specialized physiological role in [7,8], and in diet-induced thermogenesis in small rodents [9]. different plant species (reviewed in [12]). Similar to UCP2–5, pUCPs are present in plant mitochondria in low amount ..."
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The uncoupling protein (UCP) is an integral protein of the tissue specific. UCP1 has a specialized physiological role in [7,8], and in diet-induced thermogenesis in small rodents [9]. different plant species (reviewed in [12]). Similar to UCP2–5, pUCPs are present in plant mitochondria in low
The p21(Cip1) and p27(Kip1) CDK ’inhibitors’ are essential activators of cyclin D-dependent kinases in murine fibroblasts.
- EMBO J
, 1999
"... The widely prevailing view that the cyclin-dependent kinase inhibitors (CKIs) are solely negative regulators of cyclin-dependent kinases (CDKs) is challenged here by observations that normal up-regulation of cyclin D-CDK4 in mitogen-stimulated fibroblasts depends redundantly upon p21 Cip1 and p27 K ..."
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Cited by 113 (2 self)
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Kip1 . Primary mouse embryonic fibroblasts that lack genes encoding both p21 and p27 fail to assemble detectable amounts of cyclin D-CDK complexes, express cyclin D proteins at much reduced levels, and are unable to efficiently direct cyclin D proteins to the cell nucleus. Restoration of CKI function
Sugar-induced signal transduction in plants
- Plant Molecular Biology
"... Key Words hexose sensing, sucrose sensing, hexokinase, phytohormones, Arabidopsis, signal transduction n Abstract Sugars have important signaling functions throughout all stages of the plant’s life cycle. This review presents our current understanding of the different mechanisms of sugar sensing and ..."
Abstract
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Cited by 121 (1 self)
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and sugar-induced signal transduction, including the ex-perimental approaches used. In plants separate sensing systems are present for hexose and sucrose. Hexokinase-dependent and-independent hexose sensing systems can fur-ther be distinguished. There has been progress in understanding the signal
2003a) Assessment of the reliability of protein–protein interactions and protein function prediction. Pacific Symposium of Biocomputing (PSB2003
"... As more and more high-throughput protein-protein interaction data are collected, the task of estimating the reliability of different data sets becomes increasingly important. In this paper, we present our study of two groups of protein-protein interaction data, the physical interaction data and the ..."
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Cited by 93 (4 self)
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and the protein complex data, and estimate the reliability of these data sets using three different measurements: (1) the distribution of gene expression correlation coefficients, (2) the reliability based on gene ex-pression correlation coefficients, and (3) the accuracy of protein function predictions. We
and ex Vivo in
, 2008
"... Exposure to benzene elicits a spectrum of hematotoxicity ranging from reduction of peripheral blood cell counts to aplastic anemia and leukemia. The molecular mechanism by which benzene dam-ages hematopoietic cells is unclear; in particular, benzene-induced aberrant gene expression has not been addr ..."
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addressed. We analyzed differential gene expression in the peripheral white blood cells from seven female patients with occupational benzene poisoning and seven matched control subjects. In this study, we report al-tered expression of cytochrome P450 in the patients. All patients exhibited elevated
Giant peroxisomes in oleic acid-induced Saccharomyces cerevisiae lacking the peroxisomal membrane protein Pmp27p
- J. Cell
, 1995
"... Abstract. We have purified peroxisomal membranes from Saccharomyces cerevisiae after induction of peroxisomes in oleic acid-containing media. About 30 distinct proteins could be discerned among the HPLCand SDS-PAGE-separated proteins of the high salt-extracted peroxisomal membranes. The most abundan ..."
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Cited by 58 (4 self)
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abundant of these, Pmp27p, was purified and the corresponding gene PMP27 was cloned and sequenced. Its primary structure is 32 % identical to PMP31 and PMP32 of the yeast Candida biodinii (Moreno, M., R. Lark, K. L. Campbell, and M. J. Goodman. 1994. l, bast. 10:1447-1457). Immunoelectron microscopic
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the origi
"... Until recently, the role of lysosomal cysteine protease cathepsins in intracellular pro-tein degradation was believed to be mainly restricted to scavenging. However, recent studies have revealed nontraditional roles for cysteine protease cathepsins in the ex-tracellular space during the development ..."
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Cited by 106 (7 self)
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Until recently, the role of lysosomal cysteine protease cathepsins in intracellular pro-tein degradation was believed to be mainly restricted to scavenging. However, recent studies have revealed nontraditional roles for cysteine protease cathepsins in the ex-tracellular space during the development
Control of cyclin D1, p27 Kip1 and cell cycle progression in human capillary endothelial cells by cell shape and cytoskeletal tension. Mol Biol Cell
, 1998
"... The extracellular matrix (ECM) plays an essential role in the regulation of cell proliferation during angiogenesis. Cell adhesion to ECM is mediated by binding of cell surface integrin receptors, which both activate intracellular signaling cascades and mediate tension-dependent changes in cell shape ..."
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Cited by 80 (12 self)
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cells, these cells failed to progress through G1 and enter S phase. This shape-dependent block in cell cycle progression correlated with a failure to increase cyclin D1 protein levels, down-regulate the cell cycle inhibitor
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