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miRBase: integrating microRNA annotation and deep-sequencing data

by Ana Kozomara, Sam Griffiths-jones - Nucleic Acids Res , 2011
"... data ..."
Abstract - Cited by 545 (11 self) - Add to MetaCart
Abstract not found

miRBase: microRNA sequences, targets and gene nomenclature

by Sam Griffiths-jones, Russell J. Grocock, Stijn Van Dongen, Alex Bateman, Anton J. Enright - Nucleic Acids Res , 2006
"... nomenclature ..."
Abstract - Cited by 399 (5 self) - Add to MetaCart
nomenclature

A mammalian microRNA expression atlas based on small RNA library sequencing.

by Pablo Landgraf , Mirabela Rusu , Robert Sheridan , Alain Sewer , Nicola Iovino , Alexei Aravin , Sé Bastien Pfeffer , Amanda Rice , Alice O Kamphorst , Markus Landthaler , Carolina Lin , Nicholas D Socci , Leandro Hermida , Valerio Fulci , Sabina Chiaretti , Robin Foà , Julia Schliwka , Uta Fuchs , Astrid Novosel , Roman-Ulrich Mü , Bernhard Schermer , Ute Bissels , Jason Inman , Quang Phan , David B Weir , Ruchi Choksi , Gabriella De Vita , Daniela Frezzetti , Hans-Ingo Trompeter , Veit Hornung , Grace Teng , Gunther Hartmann , Miklos Palkovits , Roberto Di Lauro , Peter Wernet , Giuseppe Macino , Charles E Rogler , James W Nagle , Jingyue Ju , F Nina Papavasiliou , Thomas Benzing , Peter Lichter , Wayne Tam , Michael J Brownstein , Andreas Bosio , James J Russo , Chris Sander , Mihaela Zavolan , Thomas Tuschl - Cell, , 2007
"... SUMMARY MicroRNAs (miRNAs) are small noncoding regulatory RNAs that reduce stability and/or translation of fully or partially sequencecomplementary target mRNAs. In order to identify miRNAs and to assess their expression patterns, we sequenced over 250 small RNA libraries from 26 different organ sy ..."
Abstract - Cited by 418 (4 self) - Add to MetaCart
SUMMARY MicroRNAs (miRNAs) are small noncoding regulatory RNAs that reduce stability and/or translation of fully or partially sequencecomplementary target mRNAs. In order to identify miRNAs and to assess their expression patterns, we sequenced over 250 small RNA libraries from 26 different organ

RNA polymerase III transcribes human microRNAs.

by Glen M Borchert , William Lanier , Beverly L Davidson - Nature Struct. Mol. Biol. , 2006
"... Prior work demonstrates that mammalian microRNA (miRNA or miR) expression requires RNA polymerase II (Pol II). However, the transcriptional requirements of many miRNAs remain untested. Our genomic analysis of miRNAs in the human chromosome 19 miRNA cluster (C19MC) revealed that they are intersperse ..."
Abstract - Cited by 201 (3 self) - Add to MetaCart
Prior work demonstrates that mammalian microRNA (miRNA or miR) expression requires RNA polymerase II (Pol II). However, the transcriptional requirements of many miRNAs remain untested. Our genomic analysis of miRNAs in the human chromosome 19 miRNA cluster (C19MC) revealed

miRBase: annotating high confidence microRNAs using deep sequencing data

by Ana Kozomara , Sam Griffiths-Jones - Nucleic Acids Res , 2014
"... ABSTRACT We describe an update of the miRBase database ..."
Abstract - Cited by 167 (0 self) - Add to MetaCart
ABSTRACT We describe an update of the miRBase database

Novel and stress-regulated microRNAs and other small RNAs from Arabidopsis. Plant Cell 16

by Ramanjulu Sunkar, Jian-kang Zhu , 2004
"... MicroRNAs (miRNAs) and short interfering RNAs (siRNAs) are small noncoding RNAs that have recently emerged as important regulators of mRNA degradation, translational repression, and chromatin modification. In Arabidopsis thaliana, 43 miRNAs comprising 15 families have been reported thus far. In an a ..."
Abstract - Cited by 179 (9 self) - Add to MetaCart
MicroRNAs (miRNAs) and short interfering RNAs (siRNAs) are small noncoding RNAs that have recently emerged as important regulators of mRNA degradation, translational repression, and chromatin modification. In Arabidopsis thaliana, 43 miRNAs comprising 15 families have been reported thus far

Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans

by J. Graham Ruby, Calvin Jan, Christopher Player, Michael J. Axtell, William Lee, Chad Nusbaum, Hui Ge, David P. Bartel - Cell , 2006
"... We sequenced 400,000 small RNAs from ..."
Abstract - Cited by 143 (8 self) - Add to MetaCart
We sequenced 400,000 small RNAs from

Identification of Drosophila microRNA targets

by Er Stark, Julius Brennecke, Robert B. Russell, Stephen M. Cohen - PLoS Biol , 2003
"... MicroRNAs (miRNAs) are short RNA molecules that regulate gene expression by binding to target messenger RNAs and by controlling protein production or causing RNA cleavage. To date, functions have been assigned to only a few of the hundreds of identified miRNAs, in part because of the difficulty in i ..."
Abstract - Cited by 103 (5 self) - Add to MetaCart
MicroRNAs (miRNAs) are short RNA molecules that regulate gene expression by binding to target messenger RNAs and by controlling protein production or causing RNA cleavage. To date, functions have been assigned to only a few of the hundreds of identified miRNAs, in part because of the difficulty

MicroRNA or Not MicroRNA?

by David Langenberger, Sebastian Bartschat, Jana Hertel, Hakim Tafer, Peter F. Stadler
"... Abstract. The avalanche of next generation sequencing data has led to a rapid increase of annotated microRNAs in the last few years. Many of them are specific to individual species or rather narrow clades. A closer inspection of the current version of miRBase shows that dozens of entries conflict wi ..."
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Abstract. The avalanche of next generation sequencing data has led to a rapid increase of annotated microRNAs in the last few years. Many of them are specific to individual species or rather narrow clades. A closer inspection of the current version of miRBase shows that dozens of entries conflict

Computational and experimental identification of C. elegans microRNAs

by Yonatan Grad, John Aach, Gabriel D. Hayes, Brenda J. Reinhart, George M. Church, Gary Ruvkun, John Kim - Mol. Cell , 2003
"... MicroRNAs (miRNAs) constitute an extensive class of noncoding RNAs that are thought to regulate the expression of target genes via complementary base-pair interactions. To date, cloning has identified over 200 miRNAs from diverse eukaryotic organisms. Despite their success, such biochemical approach ..."
Abstract - Cited by 85 (0 self) - Add to MetaCart
MicroRNAs (miRNAs) constitute an extensive class of noncoding RNAs that are thought to regulate the expression of target genes via complementary base-pair interactions. To date, cloning has identified over 200 miRNAs from diverse eukaryotic organisms. Despite their success, such biochemical
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