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Results 1 - 10
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1,446
Characterization of the DNA Binding Properties of
, 1993
"... The DNA binding properties of the polyomavirus structural proteins VP1, VP2, and VP3 were studied by Southwestern analysis. The major viral structural protein VP1 and host-contributed histone proteins of polyomavirus virions were shown to exhibit DNA binding activity, but the minor capsid proteins V ..."
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The DNA binding properties of the polyomavirus structural proteins VP1, VP2, and VP3 were studied by Southwestern analysis. The major viral structural protein VP1 and host-contributed histone proteins of polyomavirus virions were shown to exhibit DNA binding activity, but the minor capsid proteins
Sequence-Specific Single-Stranded-DNA-Binding Properties of the Encoded Protein
, 1992
"... encoded protein. single-stranded-DNA-binding properties of the gene and sequence-specific Sequence of cDNA comprising the human pur ..."
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encoded protein. single-stranded-DNA-binding properties of the gene and sequence-specific Sequence of cDNA comprising the human pur
1 An Investigation of DNA-binding Properties of the Non-Receptor
"... Rlk, along with Tec family members Btk and Itk, are predominantly cytoplasmic, but have also been found localized in the nucleus. Rlk has been shown to have a specific DNA-binding relationship with the IFN-? promoter region –56/-36 region. In this study we investigate a shorter isoform of Rlk, one m ..."
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Rlk, along with Tec family members Btk and Itk, are predominantly cytoplasmic, but have also been found localized in the nucleus. Rlk has been shown to have a specific DNA-binding relationship with the IFN-? promoter region –56/-36 region. In this study we investigate a shorter isoform of Rlk, one
Helix-Loop-Helix Proteins LYL1 and E2a Form Heterodimeric Complexes with Distinctive DNA-Binding Properties in
, 1996
"... cells. DNA-binding properties in hematolymphoid heterodimeric complexes with distinctive Helix-loop-helix proteins LYL1 and E2a form ..."
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cells. DNA-binding properties in hematolymphoid heterodimeric complexes with distinctive Helix-loop-helix proteins LYL1 and E2a form
The DNA-binding properties of polyomavirus large T antigen are altered by ATP and other nucleotides
- J. Virol
, 1991
"... We have examined the influence of ATP on the DNA-binding properties of polyomavirus large T antigen (Py TAg). Utilizing nitrocellulose filter binding, DNase I footprinting, and gel mobility shift assays, we observed that ATP increased Py TAg binding to DNA fragments containing either all Py TAg-bind ..."
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Cited by 15 (5 self)
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We have examined the influence of ATP on the DNA-binding properties of polyomavirus large T antigen (Py TAg). Utilizing nitrocellulose filter binding, DNase I footprinting, and gel mobility shift assays, we observed that ATP increased Py TAg binding to DNA fragments containing either all Py TAg-binding
DNA Binding Properties of the Small Cascade Subunit
, 2014
"... CRISPR-Cas systems provide immunity against viral attacks in archaeal and bacterial cells. Type I systems employ a Cas protein complex termed Cascade, which utilizes small CRISPR RNAs to detect and degrade the exogenic DNA. A small sequence motif, the PAM, marks the foreign substrates. Previously, a ..."
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and mutants that showed decreased ssDNA-binding and reduced Cascade-mediated DNA cleavage were identified. Csa5 oligomerization prevented DNA binding. Specific recognition of the PAM sequence was not observed. Phylogenetic analyses identified Csa5 as a universal member of type I-A systems and revealed three
The DNA binding properties of Saccharomyces cerevisiae Rad51 protein
- J. Biol. Chem
, 1999
"... Saccharomyces cerevisiae Rad51 protein is the para-digm for eukaryotic ATP-dependent DNA strand ex-change proteins. To explain some of the unique charac-teristics of DNA strand exchange promoted by Rad51 protein, when compared with its prokaryotic homo-logue the Escherichia coli RecA protein, we ana ..."
Abstract
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Cited by 25 (1 self)
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analyzed the DNA binding properties of the Rad51 protein. Rad51 protein binds both single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) in an ATP- and Mg21-de-pendent manner, over a wide range of pH, with an ap-parent binding stoichiometry of approximately 1 pro-tein monomer per 4 (61) nucleotides
Solution structure and DNA-binding properties of the phosphoesterase domain of DNA ligase D
, 2011
"... The phosphoesterase (PE) domain of the bacterial DNA repair enzyme LigD possesses distinctive manganese-dependent 30-phosphomonoesterase and 30-phosphodiesterase activities. PE exemplifies a new family of DNA end-healing enzymes found in all phylogenetic domains. Here, we determined the structure of ..."
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dynamic. Chemical shift perturbations in the presence of primer-template duplexes with 30-deoxynucleotide, 30-deoxynucleotide30-phosphate,or30 ribonucleotide termini reveal the surface used byPaePE to bind sub-strate DNA and suggest amore efficient engagement in the presence of a 30-ribonucleotide
Comparison of the Structure and DNA-binding Properties of the E2 Proteins from an Oncogenic and
"... Human papillomaviruses (HPVs) that infect the genital tract can be divided into two groups: high-risk HPV types, such as HPV 16 and HPV 18, are associated with cancer, low-risk HPV types, such as HPV 6, are associated with benign warts. In both high-risk and low-risk HPV types, the papillomavirus E2 ..."
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2 protein binds to four sites within the viral long con-trol region (LCR) and regulates viral gene expression. Here, we present the crystal structure of the minimal DNA-binding domain (DBD) from the HPV 6 E2 protein. We show that the HPV 6 E2 DBD is structurally more similar to the HPV 18 and bovine
Results 1 - 10
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1,446
