Basins of Attraction in Network Dynamics: A conceptual framework for biomolecular networks (2002)
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BibTeX
@MISC{Wuensche02basinsof,
author = {Andrew Wuensche},
title = {Basins of Attraction in Network Dynamics: A conceptual framework for biomolecular networks},
year = {2002}
}
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Abstract
The state-space of a discrete dynamical network is connected into basins of attraction, mathematical objects that can be computed and shown as graphs for small networks. Multiple attractors explain how the same genetic regulatory network can maintain di#erent stable patterns of gene activation, the cell types in multi-cellular organisms. Ideas of modularity suggest that the overall genetic network is actually made up of semi-independent sub-networks. Each sub-network also settles into one of a range attractors according to its current state, which if perturbed can cause the dynamics to jump to alternative attractors.
