Measurement and standard reference materials for clinical chemistry (1968)
| Venue: | CLIN. CHEM |
| Citations: | 4 - 0 self |
BibTeX
@ARTICLE{Young68measurementand,
author = {Donald S. Young and Thomas W. Mears},
title = {Measurement and standard reference materials for clinical chemistry},
journal = {CLIN. CHEM},
year = {1968},
pages = {929}
}
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Abstract
The concepts of the measurement system based upon four parameters-length (meter), mass (kilogram), time (second), and temperature (kelvin)-are developed. The proper daily operation of an analytic laboratory depends upon these basic measure-ments and others derived from them, eg., the liter. An additional component of chemical measurement which directly influences accuracy is the purity of the standards ici reagents employed. The standard reference materials program of the National Bureau of Standards provides a central source of guaranteed high-purity reference materials which are available to all. The reliability of chemical measure-ments should increase as new standard reference materials such as cholesterol, uric acid, urea, and creatinine are utilized to standardize methoJs and to calibrate instru-ments in the clinical laboratories of this country. I_I ORD KELVIN ONCE STATED, “I often say that when you can measure what you are speaking about, and express it in numbers, you know something about it, but when you cannot measure it, when you cannot express it in numbers, your knowledge is of a meager and unsatisfactory kind....“ Although it is difficult to describe patients ’ symptoms and physical signs in terms of numbers, physicians do have quantitative data avail-able to them in measurements of temperature, pulse and respiratory rates, and blood pressure. Today, physicians also depend critically upon chemical examinations of various body fluids to provide vital quantitative data about their patients. The reliability of the chemical measurements must be assured, irrespective of their use in comparing
Keyphrases
standard reference material clinical chemistry chemical measurement proper daily operation physical sign measurement system vital quantitative data various body fluid standard reference material program blood pressure unsatisfactory kind quantitative data additional component upon chemical examination i_i ord kelvin respiratory rate chemical measure-ments new standard reference material standard ici reagent clinical laboratory patient symptom high-purity reference material central source analytic laboratory basic measure-ments uric acid national bureau
