DMCA
Antioxidant and free radical scavenging potential of (2008)
| Citations: | 9 - 0 self |
BibTeX
@MISC{Kumar08antioxidantand,
author = {Sunil Kumar and Dinesh Kumar and Kamal Saroha and Nidhan Singh and Bhoodev Vashishta},
title = {Antioxidant and free radical scavenging potential of},
year = {2008}
}
Share
 |
 |
 |
 |
||
OpenURL
Abstract
Reactive oxygen species (ROS) such as superoxide anions, hydrogen peroxide and hydroxyl, nitric oxide radicals, play an important role in oxidative stress related to the pathogenesis of various important diseases (1, 2). Antioxidants act as a major defense against radical mediated toxicity by protecting the damages caused by free radicals. An-tioxidant-based drugs/formulations for the prevention and treatment of complex disea-ses, like atherosclerosis, stroke, diabetes, Alzheimer’s disease and cancer, have appeared in the last three decades (3). This has attracted a great deal of research interest in natural antioxidants. Flavonoids and phenolic compounds are widely distributed in plants which have been reported to exert multiple biological effects, including antioxidant, free radical scavenging abilities, anti-inflammatory, anticarcinogenic, etc. (4). The aim of the present investigation was to evaluate in vitro antioxidant and free radical scavenging ac-tivity of the Citrullus colocynthis fruit extract. The fruits of Citrullus colocynthis, com-monly known as bitter apple, are bitter, acrid, cooling, cathartic, carminative, antipyre-tic, anthelmintic and are useful in hypoglycemia, tumors, ascites, leucoderma, ulcers,
Keyphrases
important role bitter apple present investigation nitric oxide radical hydrogen peroxide vitro antioxidant research interest superoxide anion citrullus colocynthis fruit extract alzheimer disease an-tioxidant-based drug formulation reactive oxygen specie various important disease free radical scavenging ability antioxidant act complex disea-ses great deal major defense natural antioxidant free radical phenolic compound citrullus colocynthis oxidative stress multiple biological effect
