Abstract

. The article at hand presents new results and conceptions concerning the intelligent and autonomous control of biotechnological processes by integrating conventional, knowledge-based and learning methods. The extended system BioX ++ facilitates the transparent generation of process control strategies and sequences based on automatically self-organized structured process models. Experimental results showing the increased product yield and the discussion of approach-specific problems are part of this paper as well as the new approaches actually examined. Key Words. Expert systems; neural networks; fuzzy systems; learning control; fermentation processes; biotechnology; genetic algorithms. 1. INTRODUCTION In contrast to fermentation control strategies based on mathematical process models in recent time a lot of research work focusses on new methods, e.g. expert systems, fuzzy logic and neural networks. Even if improvements in bioprocess control using only one of these techniques have be...

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