UniProt: the Universal Protein Knowledgebase

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UniProt: the Universal Protein Knowledgebase (2004)

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by Rolf Apweiler , Amos Bairoch , Cathy H. Wu , Winona C. Barker , Brigitte Boeckmann , Serenella Ferro , Elisabeth Gasteiger , Hongzhan Huang , Rodrigo Lopez , Michele Magrane , Maria J. Martin , Darren A. Natale , Claire O'Donovan , Nicole Redaschi , Lai-Su L. Yeh

Venue:	NUCLEIC ACIDS RES
Citations:	335 - 27 self

BibTeX

@ARTICLE{Apweiler04uniprot:the,
    author = {Rolf Apweiler and Amos Bairoch and Cathy H. Wu and Winona C. Barker and Brigitte Boeckmann and Serenella Ferro and Elisabeth Gasteiger and Hongzhan Huang and Rodrigo Lopez and Michele Magrane and Maria J. Martin and Darren A. Natale and Claire O'Donovan and Nicole Redaschi and Lai-Su L. Yeh},
    title = {UniProt: the Universal Protein Knowledgebase},
    journal = {NUCLEIC ACIDS RES},
    year = {2004},
    volume = {32},
    pages = {115--119}
}

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Abstract

To provide the scientific community with a single, centralized, authoritative resource for protein sequences and functional information, the Swiss-Prot, TrEMBL and PIR protein database activities have united to form the Universal Protein Knowledgebase (UniProt) consortium. Our mission is to provide a comprehensive, fully classified, richly and accurately annotated protein sequence knowledgebase, with extensive cross-references and query interfaces. The central database will have two sections, corresponding to the familiar Swiss-Prot (fully manually curated entries) and TrEMBL (enriched with automated classification, annotation and extensive cross-references). For convenient sequence searches, UniProt also provides several non-redundant sequence databases. The UniProt NREF (UniRef) databases provide representative subsets of the knowledgebase suitable for efficient searching. The comprehensive UniProt Archive (UniParc) is updated daily from many public source databases. The UniProt databases can be accessed online

Keyphrases

universal protein knowledgebase extensive cross-reference comprehensive uniprot archive database activity familiar swiss-prot functional information authoritative resource query interface uniprot database automated classification convenient sequence search curated entry scientific community central database protein sequence representative subset uniprot nref several non-redundant sequence database protein sequence knowledgebase many public source database

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