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Immaturities in Reward Processing and Its Influence on Inhibitory Control in Adolescence (2010)
| Citations: | 18 - 0 self |
BibTeX
@MISC{Geier10immaturitiesin,
author = {C. F. Geier and R. Terwilliger and T. Teslovich and K. Velanova and B. Luna},
title = {Immaturities in Reward Processing and Its Influence on Inhibitory Control in Adolescence},
year = {2010}
}
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Abstract
The nature of immature reward processing and the influence of rewards on basic elements of cognitive control during adolescence are currently not well understood. Here, during functional magnetic resonance imaging, healthy adolescents and adults performed a modified antisaccade task in which trial-by-trial reward contingencies were manipulated. The use of a novel fast, eventrelated design enabled developmental differences in brain function underlying temporally distinct stages of reward processing and response inhibition to be assessed. Reward trials compared with neutral trials resulted in faster correct inhibitory responses across ages and in fewer inhibitory errors in adolescents. During reward trials, the blood oxygen level--dependent signal was attenuated in the ventral striatum in adolescents during cue assessment, then overactive during response preparation, suggesting limitations during adolescence in reward assessment and heightened reactivity in anticipation of reward compared with adults. Importantly, heightened activity in the frontal cortex along the precentral sulcus was also observed in adolescents during reward-trial response preparation, suggesting reward modulation of oculomotor control regions supporting correct inhibitory responding. Collectively, this work characterizes specific immaturities in adolescent brain systems that support reward processing and describes the influence of reward on inhibitory control. In sum, our findings suggest mechanisms that may underlie adolescents ’ vulnerability to poor decision-making and risk-taking behavior.
Keyphrases
reward processing inhibitory control reward trial basic element adolescent brain system ventral striatum precentral sulcus inhibitory error cognitive control distinct stage reward-trial response preparation cue assessment functional magnetic resonance imaging response preparation risk-taking behavior antisaccade task brain function response inhibition immature reward processing neutral trial correct inhibitory correct inhibitory response blood oxygen level dependent signal reward assessment reward modulation oculomotor control region adolescent vulnerability developmental difference frontal cortex specific immaturity trial-by-trial reward contingency novel fast healthy adolescent
