Abstract

We analyze the effect of noise in integrate-and-fire neurons driven by timedependent input, and compare the diffusion approximation for the membrane potential to escape noise. It is shown that for time-dependent sub-threshold input, diffusive noise can be replaced by escape noise with a hazard function that has a Gaussian dependence upon the distance between the (noise-free) membrane voltage and threshold. The approximation is improved if we add to the hazard function a probability current proportional to the derivative of the voltage. Stochastic resonance in response to periodic input occurs in both noise models and exhibits similar characteristics.

Citations