Bioprospector: Discovering Conserved Dna Motifs In Upstream Regulatory Regions Of Co-Expressed Genes

DMCA

Bioprospector: Discovering Conserved Dna Motifs In Upstream Regulatory Regions Of Co-Expressed Genes (2001)

Cached

Download Links

Other Repositories/Bibliography

DBLP

by X. Liu , D. L. Brutlag , J. S. Liu

Venue:	Pac. Symp. Biocomput
Citations:	353 - 23 self

BibTeX

@INPROCEEDINGS{Liu01bioprospector:discovering,
    author = {X. Liu and D. L. Brutlag and J. S. Liu},
    title = {Bioprospector: Discovering Conserved Dna Motifs In Upstream Regulatory Regions Of Co-Expressed Genes},
    booktitle = {Pac. Symp. Biocomput},
    year = {2001},
    pages = {127--138}
}

OpenURL

Abstract

ms. For a copy of the program and documentation for UNIX systems, please contact xliu@smi.stanford.edu. 1 Introduction Over the last ten years, genomic sequencing has started in over 600 organisms, and over 50 complete genomes are sequenced. The DNA microarray technology permits the measurement of gene expression in cultured cells 1 . An increasing number of laboratories are using the combination of these two methods to study gene expression on a genomic scale. After all the genes from an organism are clustered based on their expression patterns 2 , an important next step is to examine the upstream region of genes in the same expression pattern group and look for sequence motifs. These motifs might be the regulatory signal (most likely a transcriptional protein binding site) that causes these genes to respond similarly to 2 developmental or environmental changes. Information on expressions, regulatory motifs and functions pro

Keyphrases

discovering conserved dna motif co-expressed gene upstream regulatory region gene expression environmental change last ten year regulatory motif transcriptional protein unix system cultured cell genomic sequencing regulatory signal expression pattern group complete genome important next step genomic scale upstream region dna microarray technology sequence motif contact xliu smi

DMCA