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Intrinsic Protein Disorder in Complete Genomes (2000)
| Citations: | 53 - 8 self |
BibTeX
@MISC{Dunker00intrinsicprotein,
author = {Keith A. Dunker and Zoran Obradovic and A. Keith and Dunker Zoran Obradovic and Pedro Romero and Ethan C. Garner and Celeste J. Brown},
title = {Intrinsic Protein Disorder in Complete Genomes},
year = {2000}
}
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Abstract
Intrinsic protec disorde reord toseDO: ts or towhole prote%k that fail to foldcomplejDE onthej own. HeE we preO:kEb disorde onproteO seteO[E from 34gek:]O[ including 22 bacteDk[ 7 archae% and 5eD:%# ote% Pre%#8Eb disorde8] sesor ts # 50, # 40, and # 30 in leEO% we% deD#:Eb8[ as weD asprote#k eote#kE to be whollydisordeD]: The five eEkO] otewe] seD#Eb8# frombacte#D and archae by havingthe highe: pe8j[ tage ofsekDkkkE preDkkkE to have disorde8j sesor ts # 50 inleDk]: from 25% for Plasmodium to 41% for Drosophila. Estimate of whollydisorde:% protede inthe bactej[ range from 1% to 8%, avek8Oj% to 32%, e%,EO%D8 in various archae range from 2 to 11%, plus anappare tly anomalous 18%, avek[%%O to 75% that drops to 53% ifthe high value isdiscarde8 Estimate inthe 5ekD%[ arange from 3 to 17%.The putative whollydisorde:k protede we8 ofte ribosomalproteEk: but in addition abouteE%% numbe% we% of known and unknown function. OveE8jk intrinsic disorde app to be a common, withethE% ote peDDO# having ahighe pe888 tage of native disorde than archae or bacte#Eb Keywords: intrinsicdisorde% prede%O]: structuralgeructu 1
Keyphrases
intrinsic protein disorder complete genome towhole prote intrinsicdisorde prede ote pre ifthe high value isdiscarde8 estimate native disorde withethe ote peddo addition aboutee disorde8j sesor ovee8jk intrinsic disorde app otewe sed eb8 frombacte eo d8 bacte eb keywords intrinsic protec disorde reord tosedo havingthe highe protede inthe bactej range wed asprote we8 ofte ribosomalproteek pe8j tage ofsekdkkke predkkke ahighe pe888 tage putative whollydisorde disorde8 sesor t unknown function various archae range keb disorde onproteo seteo
