Abstract

this paper, we describe the construction of parametric surface skins using real spherical polar basis functions. As the use of such functions for protein shape representation is novel, a brief summary of their properties is also provided. We then give a description of the algebraic manipulations necessary to develop an efficient search for docking orienta- tions by incrementally rotating and translating the parametric representations. We also show that this spherical polar approach provides a natural way to model macromolecular electrostatic complementarity

Citations