Inferring a duplication, speciation and loss history from a gene tree (2007)
| Venue: | In Fifth RECOMB International Workshop on Comparative Genomics |
| Citations: | 6 - 3 self |
BibTeX
@INPROCEEDINGS{Chauve07inferringa,
author = {Cedric Chauve and Nadia El-mabrouk},
title = {Inferring a duplication, speciation and loss history from a gene tree},
booktitle = {In Fifth RECOMB International Workshop on Comparative Genomics},
year = {2007}
}
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Abstract
Abstract. We consider two questions related to the evolution of gene families. First, given a gene tree for a gene family, can the evolutionary history of this family be explained with only speciation and duplication events, and without gene loss. We show that this question can be answered in linear time, and that such a gene tree induces a single species tree consistent with a history with no loss. We then present a heuristic for the following problem: if a gene tree can not be explained without gene loss, what is the minimum number of losses involved in an evolutionary history of the gene family. We finally evaluate our algorithms on a dataset of plants gene families. 1
