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A Biophysical Model of Decision Making in an Antisaccade Task Through Variable Climbing Activity
| Citations: | 2 - 2 self |
BibTeX
@MISC{Cutsuridis_abiophysical,
author = {Vassilis Cutsuridis and Ioannis Kahramanoglou and Stavros Perantonis and Ioannis Evdokimidis and Nikolaos Smyrnis},
title = {A Biophysical Model of Decision Making in an Antisaccade Task Through Variable Climbing Activity},
year = {}
}
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Abstract
Abstract. We present a biophysical model of saccade initiation based on competitive integration of planned and reactive cortical saccade decision signals in the intermediate layer of the superior colliculus. In the model, the variable slopes of the climbing activities of the input cortical decision signals are produced from variability in the conductances of Na +, K +, Ca 2+ activated K +, NMDA and GABA currents. These cortical decision signals are integrated in the activities of buildup neurons in the intermediate layer of the superior colliculus, whose activities grow nonlinearly towards a preset criterion level. When the level is crossed, a movement is initiated. The resultant model reproduces the unimodal distributions of saccade reaction times (SRTs) for correct antisaccades and erroneous prosaccades as well as the variability of SRTs (ranging from 80ms to 600ms) and the overall 25 % of erroneous prosaccade responses in a large sample of 2006 young men performing an antisaccade task. 1
Keyphrases
biophysical model decision making antisaccade task variable climbing activity superior colliculus intermediate layer gaba current large sample reactive cortical saccade decision signal antisaccade task saccade reaction time cortical decision signal input cortical decision signal preset criterion level correct antisaccades unimodal distribution erroneous prosaccade response competitive integration buildup neuron saccade initiation young men variable slope resultant model erroneous prosaccades
