BibTeX
@MISC{_vascular,
author = {},
title = {VASCULAR},
year = {}
}
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Abstract
Full list of author information is available at the end of the articleBackground Myocardial infarction (MI) and diabetes mellitus (DM) are serious diseases with high morbidity and mortality. It was estimated in 2010 that there were almost 1,000,000 patients with MI in the USA, with a 3-year mortality of nearly 25 % [1]. Diabetes mellitus has been widely recog-nized as a major risk factor for cardiovascular disease, and carries the same risk of mortality as MI itself [2]. Previous studies have demonstrated that the prognosis of the coronary artery disease (CAD) in patients with DM is significantly worse than in patients with CAD alone [3]. However, the mechanisms that underlie this observation are not fully understood. Mesenchymal stem cells (MSCs) transplantation has been widely used as an effective method of protecting the damaged myocardium and improving cardiac func-tion [4]. MSCs can be readily isolated from bone mar-row, adipose tissue, and umbilical cord blood. Ex vivo experiments indicate that MSCs express CD105, CD73, CD90, CD29 and CD166, but lack expression of CD45,
Keyphrases
major risk factor articlebackground myocardial infarction full list 3-year mortality ex vivo experiment previous study serious disease cardiac func-tion mesenchymal stem cell adipose tissue author information umbilical cord blood bone mar-row high morbidity msc express cd105 effective method coronary artery disease cardiovascular disease
