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Chronic Stress, Aging and Morphine Analgesia: Chronic Stress Affects the Reactivity to Morphine in Young Mature but not Old Rats1
by
Maria-Nadia Girardor
,
Frank A Holloway
BibTeX
@MISC{Girardor_chronicstress,,
author = {Maria-Nadia Girardor and Frank A Holloway},
title = {Chronic Stress, Aging and Morphine Analgesia: Chronic Stress Affects the Reactivity to Morphine in Young Mature but not Old Rats1},
year = {}
}
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Abstract
ABSTRACT The effect of chronic stress on analgesic responsiveness to morphine was studied in mature rats of different ages. Chronic stress consisted of eighteen 1 0-sec exposures (three/mm) in 2#{176}C water for 54 consecutive days. From day 20, at 4-day intervals, the rats were not stressed but instead given i.p. injections of, sequentially: 10, 0 (saline), 5, (2 mg/kg of naltrexone)
