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The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000 (2000)
| Venue: | Nucleic Acids Res |
| Citations: | 772 - 21 self |
BibTeX
@ARTICLE{Bairoch00theswiss-prot,
author = {Amos Bairoch and Rolf Apweiler},
title = {The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000},
journal = {Nucleic Acids Res},
year = {2000},
volume = {27},
pages = {49--54}
}
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Abstract
SWISS-PROT is a curated protein sequence database which strives to provide a high level of annotation (such as the description of the function of a protein, its domains structure, post-translational modifications, variants, etc.), a minimal level of redundancy and high level of integration with other databases. Recent developments of the database include format and content enhancements, cross-references to additional databases, new documentation files and improvements to TrEMBL, a computer-annotated supplement to SWISS-PROT. TrEMBL consists of entries in SWISS-PROT-like format derived from the translation of all coding sequences (CDSs) in the EMBL Nucleotide Sequence Database, except the CDSs already included in SWISS-PROT. We also describe the Human Proteomics Initiative (HPI), a major project to annotate all known human sequences according to the quality standards of SWISS-PROT. SWISS-PROT is available at: http://www.expasy.ch/sprot/ and http:// www.ebi.ac.uk/swissprot/
Keyphrases
swiss-prot protein sequence database supplement trembl high level new documentation file curated protein sequence database swiss-prot-like format human proteomics initiative recent development embl nucleotide sequence database human sequence minimal level domain structure coding sequence quality standard major project ch sprot uk swissprot computer-annotated supplement post-translational modification content enhancement additional database
