Abstract

Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. A primary infection in a remote site resulting in vision threatening complications like panophthalmitis in a person who is not immune-compromised is rare.We report a case of endogenous bilateral bacterial endophthalmitis progressing into panophthalmitis in one eye requiring evisceration of that eye. A patient admittedwith severe ESBLE. coli urosepsis was effectively treatedwith source control (bilateral DJ stenting for hydroureteronephrosis) and antibiotics. She was found to have features suggestive of bilateral conjunctivitis which progressed to panophthalmitis possibly due to delay in appropriate diagnosis and treatment.Diagnosis requires a very high index of suspicion if eye involvement is noted in a patient with features of bacteraemia and early intervention could possibly produce better outcomes. To our knowledge, this is the first case of ESBL E. coli urosepsis complicated bymicrobiologically confirmed panophthalmitis. 1.