Abstract

Summary: In recent years, the improvement of mass spectrometry-based glycomics techniques (i.e., highly sensitive, quantitative and high-throughput analytical tools) has enabled us to obtain a large dataset of glycans. Here we present a database named Xeno-glycomics database (XDB) that contains cell- or tissue-specific pig glycomes analyzed with mass spectrometry-based techniques, in-cluding a comprehensive pig glycan information on chemical struc-tures, mass values (m/z), types, relative quantities. It was designed as a user-friendly, web-based interface which allows user to query the database according to pig tissue/cell types or glycan masses. This database will contribute in providing qualitative and quantitative information on glycomes characterized from various pig cells/organs in xenotransplantation and might eventually provide new targets in the α1,3-galactosyltransferase (GalT) gene-knock out (KO) pigs era. Availability: The database can be accessed on the web at