Citation Context

...thelial cells. The intra-glomerular renal lymphoma (IGRL) was seen in only 20% of the cases reported so far. It is also called malignant intravascular lymphomatosis or angiotropic large-cell lymphoma =-=[6]-=-. Patients usually present with nephrotic-range proteinuria, normal-sized kidneys, and a milder renal failure as compared with the IRL type. The latter is primary because the infiltration is limited t...

Citation Context

...entional imaging (due to diffuse infiltration of the kidney), and the lymphoma should be the primary cause of renal failure (e.g. lymphoma-associated renal failure and lymphomaassociated proteinuria) =-=[2]-=-. This entity therefore does not include those cases where the tumor presented as a discrete kidney mass, thus warranting further investigation of a suspected tumor. Renal lymphoma is commonly a diffu...

Citation Context

...l and squamous cell carcinoma) invading the renal parenchyma, renal lymphoma, squamous cell carcinoma (from lung) metastasizing to the kidney and infiltrating sarcomatous type of renal cell carcinoma =-=[1]-=-. To be classified as a typical case of renal lymphoma, the lymphoma should have gone unnoticed on conventional imaging (due to diffuse infiltration of the kidney), and the lymphoma should be the prim...

Citation Context

...tion of a suspected tumor. Renal lymphoma is commonly a diffuse large-cell lymphoma and is predominantly of B-cell lineage (nonHodgkin’s lymphoma) with T-cell immunophenotype seen in only a few cases =-=[3]-=-. Based on renal biopsy, renal lymphomas can be of two broad histological patterns—interstitial or intra-glomerular. These varieties have distinct presentation and histological characteristics. Of the...

Citation Context

...rn was noted in 80% of the cases, and the latter in only 20%. One recent report suggested that intra-glomerular lymphoma may transform into a diffuse type also infiltrating extraglomerular structures =-=[4]-=-. Apart from the usual presenting symptoms of acute renal failure, like generalized weakness, nausea (depending on the BUN) and anorexia, the patient may have night sweats, back pain and weight loss. ...

Citation Context

...d cells is the primary cause of renal failure as it leads to increased intra-renal pressure, tubular compression and increased peri-tubular capillary pressure, and therefore also decreases in the GFR =-=[5]-=-. The glomeruli are normal, and the tubules are devoid of any injury to the epithelial cells. The intra-glomerular renal lymphoma (IGRL) was seen in only 20% of the cases reported so far. It is also c...

Citation Context

...ted. The likely mechanism for nephrotic-range proteinuria in patients with intra-glomerular lymphoma is probably related to the local release of permeability-enhancing cytokines by the lymphoma cells =-=[7]-=-. The histological differential diagnoses for IRL include interstitial nephritis and diffuse infiltrative lymphocytosis syndrome, whereas IGRL is more likely to be confused with endocapillary prolifer...

Citation Context

...ential diagnoses for IRL include interstitial nephritis and diffuse infiltrative lymphocytosis syndrome, whereas IGRL is more likely to be confused with endocapillary proliferative glomerulonephritis =-=[8]-=-. In both IRL and IGRL, the atypical appearance of the infiltrate should prompt an immunohistochemical work-up that would reveal the true lymphomatous nature of the process [4]. The treatment of acute...