Citations
67 |
The critical size defect as an experimental model for craniomandibulofacial nonunions.
- JP, JO
- 1986
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Citation Context ...est intraosseous wound in an animal that will not heal spontaneously when left untreated for a certain time period [1] or which shows less than 10% bone regeneration during the lifetime of the animal =-=[2]-=-. The CSD has been used as an experimental model for evaluating the effectiveness of newly developed biomaterials [3]. There are several bone defect models, including those for the tibia, radius, mand... |
22 |
The potential of sheep for the study of osteopenia: current status and comparison with other animal models
- Newman, AS, et al.
- 1995
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Citation Context ... 181 JPIS & Implant Science phase bone model for experiments related to bone graft materials and evaluations of bone regeneration due to the adequate amount of bone marrow facilitating bone formation =-=[7,8]-=-. Moreover, the rabbit has a larger cranium than the rat, which makes it possible to create multiple defects in one cranium, which reduces the operation time, cost, and observational errors among indi... |
8 |
A convenient animal model for testing bone substitute materials.
- JW
- 1980
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Citation Context ...ong them, a cranial defect provides a model for non-load-bearing bone with relative biological inertness due to its poor blood supply and limited bone marrow, thereby resembling human mandibular bone =-=[4]-=-. Thus, cranial defects in validated small-animal models have been used in numerous studies for evaluating newly developed biomaterials for implantations prior to performing large-animal implantations... |
6 |
et al. Reconstruction of calvarial defect of rabbits using porous calcium silicate bioactive ceramics. Biomaterials
- Xu, Lin, et al.
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Citation Context ...ne and membrane materials have been reported. Some researchers have evaluated bone regeneration of rectangular (10 × 10 mm) cranial defects, which were used as CSDs [9,10], and 10-mm circular defects =-=[11]-=-. In addition, 8- and 6-mm circular defects have generally been used when observing the effects of barrier membranes and bone graft materials [12-15]. Circular 15-mm defects also have been used as the... |
5 |
Diaz-Curiel M, et al. Bone mineral measurements of subchondral and trabecular bone in healthy and osteoporotic rabbits. Skeletal Radiol
- Castaneda, Largo, et al.
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Citation Context ... 181 JPIS & Implant Science phase bone model for experiments related to bone graft materials and evaluations of bone regeneration due to the adequate amount of bone marrow facilitating bone formation =-=[7,8]-=-. Moreover, the rabbit has a larger cranium than the rat, which makes it possible to create multiple defects in one cranium, which reduces the operation time, cost, and observational errors among indi... |
5 | Guided bone regeneration of cranial defects, using biodegradable barriers: an experimental pilot study in the rabbit. J Cranio-maxillo-facial Surg - Lundgren, Nyman, et al. - 1992 |
4 |
et al. Effect of sex steroids on peak bone density of growing rabbits
- Gilsanz, TF, et al.
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Citation Context ... [5]. The rabbit is commonly used in animal experiments for medical research. Some of its advantages are that it is easily handled, has a rapid bone turnover rate, and is fully mature within 6 months =-=[6]-=-. Rabbit cranial defects provide a good first Received: May. 3, 2010; Accepted: Jul. 13, 2010 *Correspondence: Seong-Ho Choi Department of Periodontology, Research Institute for Periodontal Regenerati... |
4 | Mulliken JB. Fate of mineralized and demineralized osseous implants in cranial defects. Calcif Tissue Int - Glowacki, Altobelli - 1981 |
3 |
Spauwen PH, Mikos AG, Jansen JA. Closing capacity of segmental radius defects in rabbits
- EW
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Citation Context ...] or which shows less than 10% bone regeneration during the lifetime of the animal [2]. The CSD has been used as an experimental model for evaluating the effectiveness of newly developed biomaterials =-=[3]-=-. There are several bone defect models, including those for the tibia, radius, mandible, and cranium. Among them, a cranial defect provides a model for non-load-bearing bone with relative biological i... |
3 |
Goyenvalle E, Aguado E, HouchmandCuny M, Enkel B, Pilet P, Daculsi G, Layrolle P. Small-animal models for testing macroporous ceramic bone substitutes
- Guehennec
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Citation Context ... Thus, cranial defects in validated small-animal models have been used in numerous studies for evaluating newly developed biomaterials for implantations prior to performing large-animal implantations =-=[5]-=-. The rabbit is commonly used in animal experiments for medical research. Some of its advantages are that it is easily handled, has a rapid bone turnover rate, and is fully mature within 6 months [6].... |
3 |
TD, Song L-S, Capel CC, Sudhakar PV, Matloub HS. Osteogenesis in calvarial defects: contributions of dura, the pericranium, and the surrounding bone in adult versus infant animals. Plast Reconstr Surg 2003;112:515–527
- AK, Santoro
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Citation Context ...ape of rabbit cranial defects on bone and membrane materials have been reported. Some researchers have evaluated bone regeneration of rectangular (10 × 10 mm) cranial defects, which were used as CSDs =-=[9,10]-=-, and 10-mm circular defects [11]. In addition, 8- and 6-mm circular defects have generally been used when observing the effects of barrier membranes and bone graft materials [12-15]. Circular 15-mm d... |
3 | Mazzonetto R, de Moraes M, Moreira RW. Histological and histomorphometric analyses of calcium phosphate cement in rabbit calvaria - SC, CL |
3 | Tresguerres IF, Alkhraisat MH, Khraisat A, Lopez-Cabarcos E, Blanco L. Effect of solely applied platelet-rich plasma on osseous regeneration compared to Bio-Oss: A morphometric and densitometric study on rabbit calvaria. Clin Implant Dent Relat Res - Torres, FM - 2008 |
2 |
AE, Heiple KG, Zika JM. The effect of histocompatibility matching on canine frozen bone allografts. J Bone Joint Surg Am
- GD, VM, et al.
- 1983
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Citation Context ...nd healing. INTRODUCTION The critical size defect (CSD) has been defined as the smallest intraosseous wound in an animal that will not heal spontaneously when left untreated for a certain time period =-=[1]-=- or which shows less than 10% bone regeneration during the lifetime of the animal [2]. The CSD has been used as an experimental model for evaluating the effectiveness of newly developed biomaterials [... |
2 |
Nuntanaranont T, Vongvatcharanon S. Proportion of deproteinized bovine bone and autogenous bone affects bone formation in the treatment of calvarial defects in rabbits
- Pripatnanont
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Citation Context ...ape of rabbit cranial defects on bone and membrane materials have been reported. Some researchers have evaluated bone regeneration of rectangular (10 × 10 mm) cranial defects, which were used as CSDs =-=[9,10]-=-, and 10-mm circular defects [11]. In addition, 8- and 6-mm circular defects have generally been used when observing the effects of barrier membranes and bone graft materials [12-15]. Circular 15-mm d... |
2 | AJ, Lang NP. Osseous healing of experimentally created defects in the calvaria of rabbits using guided bone regeneration. A pilot study. Clin Oral Implants Res - CH, Schmid, et al. - 1992 |
2 |
A histological and radiological comparison of the healing of defects in the rabbit calvarium with and without implanted heterogeneous anorganic bone. Arch Oral Biol 1968;13:1095–1106
- IR, HC, et al.
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Citation Context ...terials [16-18]. However, few studies have analyzed the healing capacity histometrically in defects of different sizes over time. Whilst the CSD of the rabbit cranium has been investigated previously =-=[4,13]-=-, its size and shape have not been standardized. Therefore, the purpose of this study was to measure the spontaneous healing capacity of surgically produced cranial defects in rabbits at different hea... |
2 | Allogeneic bone grafting of calvarial defects: an experimental study - JM, AA, et al. |
2 |
Bosco AF, Ribeiro LL, Leite CM. Bone healing in surgically created defects treated with either bioactive glass particles, a calcium sulfate barrier, or a combination of both materials. A histological and histometric study in rat tibias.Clin Oral Implants
- LG, MJ
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Citation Context ...the right and left margins of the surgical defect, and then connecting them with lines drawn by extrapolating from their respective curvatures. This method was partly based on the work of Melo et al. =-=[19]-=-. The total area was taken as 100% of the area to be analyzed. 3) �New bone ingrowth (mm) = (sum of new bone ingrowth, mm)/2. The average length of the new bone was measured from the right and left ma... |
2 |
Mehrara BJ, Spector JA, Chin GS, Steinbrech DS, Saadeh PB et al. Biomolecular mechanisms of calvarial bone induction: immature versus mature dura mater. Plast Reconstr Surg 2000;105:1382–1392
- JA
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Citation Context ...steum. The periosteum provides cortical bone with a blood supply [1,2], and the dura mater has been demonstrated to contribute to the reossification of cranial defects due to its osteogenic potential =-=[27]-=-. However, the dura mater can be easily damaged when creating defects, and hence the healing of cranial defects is usually accomplished from the defect edge and periosteum.186 Healing capacity of rab... |
2 |
SH, Zhu SJ, Jung JH. Critical size defect in the canine mandible. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2005
- JY, BH, et al.
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Citation Context ...nial defects is usually accomplished from the defect edge and periosteum.186 Healing capacity of rabbit cranial defects for CSD determination Journal of Periodontal JPIS & Implant Science Huh et al. =-=[28]-=- showed that the CSD depends on the presence of the periosteum and considered it necessary to differentiate CSDs according to whether the periosteum is present. In the present study, the dura mater of... |
1 | Aaboe M, Hjorting-Hansen E, Nattestad A, Melsen F. Influence of particle size of autogenous bone grafts on the early stages of bone regeneration: a histologic and stereologic study in rabbit calvarium - Pallesen, Schou |
1 | Hand-held computers in medicine - Cameron |
1 | Messora MR, Bomfim SR, Fucini SE, Garcia VG, et al. Effect of platelet-rich plasma on bone healing of autogenous bone grafts in critical-size defects - MJ, LG |
1 | Evaluation of the biocompatibility and osteoproductive activity of ostrich eggshell powder in experimentally induced calvarial defects in rabbits - Durmus, Celik, et al. |
1 | Osteogenesis in cranial defects and diffusion chambers. Comparison in rabbits of bone matrix, marrow, and collagen implants. Acta Orthop Scand - BS, JF |
1 | Schmalzreid T, et al. Bone regeneration under the influence of a bone morphogenetic protein (BMP) beta tricalcium phosphate (TCP) composite in skull trephine defects in dogs. Clin Orthop Relat Res - MR, Nilsson, et al. |
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Deutsche Gesellschaft fur Chirurgie. Bernhard Heines Versuche uber Knochenregeneration: sein Leben und seine Zeit
- KT, Redenz, et al.
- 1926
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Citation Context ...es of experimental defects and the healing period. Some radiographs obtained in the present study showed bony islets in the central area of defects that were away from the defect edge. Vogeler et al. =-=[26]-=- reported differences in osteogenesis between central and peripheral new bone within cranial defects, and found that regeneration in cranial defects occurred both from the cut edges of the bone and fr... |