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Correspondence to
, 2013
"... Are physiological changes experienced by healthy subjects during acu-TENS associated with acupuncture point sensations? ..."
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Are physiological changes experienced by healthy subjects during acu-TENS associated with acupuncture point sensations?
Address for Correspondence:
"... D ow nloaded from DOI: 10.1161/CIRCULATIONAHA.114.014149 2 Nitrate accumulates in the plasma from oral intake of foods rich in nitrate, such as green leafy vegetables and root plants like beet root, or from the intravascular oxidation of NO, produced by the NO synthase enzymes, to nitrate by oxyhemo ..."
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D ow nloaded from DOI: 10.1161/CIRCULATIONAHA.114.014149 2 Nitrate accumulates in the plasma from oral intake of foods rich in nitrate, such as green leafy vegetables and root plants like beet root, or from the intravascular oxidation of NO, produced by the NO synthase enzymes, to nitrate by oxyhemoglobin. Nitrate is then concentrated in the saliva and reacts with oral commensal bacteria which contain nitrate reductase enzymes.1 Humans do not possess nitrate reductase enzymes so require these bacteria for conversion of nitrate to nitrite. Nitrite is then swallowed and systemically absorbed where it can be further reduced via one-electron transfer reactions with hemoglobin, myoglobin, neuroglobin and molybopterrin-containing enzymes (such as xanthine oxidase, aldehyde oxidase and mARC).2-7 This is now referred to as the nitrate-nitrite-NO pathway and involves a series of oxygen-independent and NO synthase independent single electron transfer reactions (Figure 1A).
beagles
, 2003
"... A canine model for human monocytic ehrlichiosis was used to assess persistent infection and antigenic variation of Ehrlichia chaffeensis. Two beagle dogs were infected subcutaneously with E. chaffeensisArkansas strain. The dogs were observed for 6 months after inoculation for clinical signs, blood c ..."
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A canine model for human monocytic ehrlichiosis was used to assess persistent infection and antigenic variation of Ehrlichia chaffeensis. Two beagle dogs were infected subcutaneously with E. chaffeensisArkansas strain. The dogs were observed for 6 months after inoculation for clinical signs, blood chemistry changes, antibodies to E. chaffeensis and presence of E. chaffeensis in the blood. Both dogs developed thrombocytopenia, but exhibited normal body temperatures during the entire course of infection. In one dog, E. chaffeensiswas cultivated for up to 74 days post-inoculation and E. chaffeensis DNA was detected in the dog’s blood for up to 81 days. In the other dog, E. chaffeensis was cultured for up to 102 days and E. chaffeensis DNA was detected in the blood for up to 117 days. PCR amplification and DNA sequence analysis indicated that there was no genetic variation in the 120 kDa outer-membrane glycoprotein gene of E. chaffeensis during infection of the dogs. The dogs developed antibodies to the immunodominant proteins of E. chaffeensis, including
A Community Lost: Urban Renewal and Displacement in San Francisco’s Western Addition District
, 2008
"... will sunset. According to the Redevelopment Agency’s website, the original purpose of the project was “to reduce blight by making building and streetscape improvements that would attract new business customers, residents and visitors to the Fillmore, ” and their work in the ..."
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will sunset. According to the Redevelopment Agency’s website, the original purpose of the project was “to reduce blight by making building and streetscape improvements that would attract new business customers, residents and visitors to the Fillmore, ” and their work in the
Correspondence
, 2004
"... JC virus (JCV) is a double-stranded DNA polyomavirus co-evolving with humans since the time of their origin in Africa. JCV seems to provide new insights into the history of human populations, as it suggests an expansion of humans from Africa via two distinct migrations, each carrying a different lin ..."
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JC virus (JCV) is a double-stranded DNA polyomavirus co-evolving with humans since the time of their origin in Africa. JCV seems to provide new insights into the history of human populations, as it suggests an expansion of humans from Africa via two distinct migrations, each carrying a different lineage of the virus. A possible alternative to this interpretation could be that the divergence between the two lineages is due to selective pressures favouring adaptation of JCV to different climates, thus making any inference about human history debatable. In the present study, the evolution of JCV was investigated by applying correspondence analysis to a set of 273 fully sequenced strains. The first and more important axis of ordination led to the detection of 61 nt positions as the main determinants of the divergence between the two virus lineages. One lineage includes strains of types 1 and 4, the other strains of types 2, 3, 7 and 8. The distinctiveness of the Caucasian lineage (types 1 and 4), largely diffused in the northern areas of the world, was almost entirely ascribed to synonymous substitutions. The findings provided by the subsequent axes of ordination supported the view of an evolutionary history of JCV characterized by genetic drift and migration, rather than by natural selection. Correspondence analysis was also applied to a set of 156 human mitochondrial genome sequences. A detailed comparison between the substitution patterns in JCV and mitochondria brought to light some relevant advantages of the use of the virus in tracing human migrations.
Class of 2014
, 2014
"... Obtaining unpaid summer internships is increasingly popular among undergraduates, who feel pressure to accumulate as much work experience as possible during college to improve their chances of securing a good job after graduation. Some students are willing to accept unpaid internships because they a ..."
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Obtaining unpaid summer internships is increasingly popular among undergraduates, who feel pressure to accumulate as much work experience as possible during college to improve their chances of securing a good job after graduation. Some students are willing to accept unpaid internships because they anticipate these experiences will enable them to gain insight into the inner-workings of a particular field, learn professionally valuable skills, and expand networking opportunities. Others are compelled to saturate their resumes with unpaid internships due to feelings of anxiety and desperation related to job insecurity in the current economy. These are just some of the factors that have contributed to the considerable growth of unpaid internships in recent years. According to estimates by the Intern Bridge research firm, undergraduates currently undertake over 1 million internships annually, half of which are unpaid (Greenhouse 2013). Reports published by Intern Bridge suggest that 70-75 percent of students at four-year colleges now undertake one or more internships, which is at least double the amount in the early 1980s (Perlin 2011: 26). This upsurge has raised concerns within the media, federal government,
David PhillipsFeeling in the Public Sphere: A study of emotion, public discourse, and
"... the law in the murders of James Byrd Jr. and Matthew Shepard ..."
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