Results 1 -
5 of
5
Differential Effects of Motor Efference Copies and Proprioceptive Information on Response Evaluation Processes
, 2013
"... It is well-kown that sensory information influences the way we execute motor responses. However, less is known about if and how sensory and motor information are integrated in the subsequent process of response evaluation. We used a modified Simon Task to investigate how these streams of information ..."
Abstract
-
Cited by 1 (0 self)
- Add to MetaCart
(Show Context)
It is well-kown that sensory information influences the way we execute motor responses. However, less is known about if and how sensory and motor information are integrated in the subsequent process of response evaluation. We used a modified Simon Task to investigate how these streams of information are integrated in response evaluation processes, applying an in-depth neurophysiological analysis of event-related potentials (ERPs), time-frequency decomposition and sLORETA. The results show that response evaluation processes are differentially modulated by afferent proprioceptive information and efference copies. While the influence of proprioceptive information is mediated via oscillations in different frequency bands, efference copy based information about the motor execution is specifically mediated via oscillations in the theta frequency band. Stages of visual perception and attention were not modulated by the interaction of proprioception and motor efference copies. Brain areas modulated by the interactive effects of proprioceptive and efference copy based information included the middle frontal gyrus and the supplementary motor area (SMA), suggesting that these areas integrate sensory information for the purpose of response evaluation. The results show how motor response evaluation
Neuropsychologia 50 (2012) 2477–2491 Contents lists available at SciVerse ScienceDirect
"... journal homepage: www.elsevier.com/locate/neuropsychologia Recall deficits in stroke patients with thalamic lesions covary with damage ..."
Abstract
- Add to MetaCart
(Show Context)
journal homepage: www.elsevier.com/locate/neuropsychologia Recall deficits in stroke patients with thalamic lesions covary with damage
RESEARCH ARTICLE Changes in Thalamic Connectivity in the Early and Late Stages of Amnestic Mild Cognitive Impairment: A Resting-State Functional Magnetic Resonance Study from
"... ¶ Information on the Alzheimer’s disease Neuroimaging Initiative (ADNI) is provided in the Acknowledgments We used resting-state functional magnetic resonance imaging (fMRI) to investigate changes in the thalamus functional connectivity in early and late stages of amnestic mild cognitive impairment. ..."
Abstract
- Add to MetaCart
(Show Context)
¶ Information on the Alzheimer’s disease Neuroimaging Initiative (ADNI) is provided in the Acknowledgments We used resting-state functional magnetic resonance imaging (fMRI) to investigate changes in the thalamus functional connectivity in early and late stages of amnestic mild cognitive impairment. Data of 25 late stages of amnestic mild cognitive impairment (LMCI) patients, 30 early stages of amnestic mild cognitive impairment (EMCI) patients and 30 well-matched healthy controls (HC) were analyzed from the Alzheimer’s disease Neuroim-aging Initiative (ADNI). We focused on the correlation between low frequency fMRI signal fluctuations in the thalamus and those in all other brain regions. Compared to healthy con-trols, we found functional connectivity between the left/right thalamus and a set of brain areas was decreased in LMCI and/or EMCI including right fusiform gyrus (FG), left and right superior temporal gyrus, left medial frontal gyrus extending into supplementary motor area, right insula, left middle temporal gyrus (MTG) extending into middle occipital gyrus (MOG). We also observed increased functional connectivity between the left/right thalamus and several regions in LMCI and/or EMCI including left FG, right MOG, left and right precuneus,
RESEARCH ARTICLE Altered Functional Connectivity in Patients with Subcortical Vascular Cognitive Impairment—A Resting-State Functional Magnetic Resonance Imaging Study
"... Recent neuroimaging studies have shown that people with subcortical vascular cognitive impairment (sVCI) have structural and functional abnormalities in the frontal lobe and sub-cortical brain sites. In this study, we used seed-based resting-state functional connectivity (rsFC) analysis and voxel-mi ..."
Abstract
- Add to MetaCart
(Show Context)
Recent neuroimaging studies have shown that people with subcortical vascular cognitive impairment (sVCI) have structural and functional abnormalities in the frontal lobe and sub-cortical brain sites. In this study, we used seed-based resting-state functional connectivity (rsFC) analysis and voxel-mirrored homotopic connectivity (VMHC) techniques to investi-gate the alteration of rsFC in patients with sVCI. rsFC and structural magnetic resonance images were acquired for 51 patients with subcortical cerebrovascular disease. All patients were subdivided based on cognitive status into 29 with sVCI and 22 controls; patient char-acteristics were matched. rsFC of the posterior cingulate cortex (PCC) and VMHC were calculated separately, and rsFC of the PCC and VMHC between the two groups were com-pared. The regions showing abnormal rsFC of the PCC or VMHC in sVCI patients were adopted as regions of interest for correlation analyses. Our results are as follows: The patients with sVCI exhibited increases in rsFC in the left middle temporal lobe, right inferior temporal lobe and left superior frontal gyrus, and significant decreases in rsFC of the left thalamus with the PCC. sVCI patients showed a significant deficit in VMHC between the bilateral lingual gyrus, putamen, and precentral gyrus. Additionally, the z-memory score was significantly positively associated with connectivity between the left thalamus and the PCC (r = 0.41, p = 0.03, uncorrected) in the sVCI group. Our findings suggest that the frontal lobe and subcortical brain sites play an important role in the pathogenesis of sVCI. Further-more, rsFC between the left thalamus and the PCCmight indicate the severity of sVCI.
dA
, 2013
"... is a with schizophrenia often show impairments in their ability to monitor their ongoing behavior, and to adjust their responses based on advance information or feedback. By conducting a systematic examination of the behav-implicated as a major precise nature of its els propose that the atible respo ..."
Abstract
- Add to MetaCart
(Show Context)
is a with schizophrenia often show impairments in their ability to monitor their ongoing behavior, and to adjust their responses based on advance information or feedback. By conducting a systematic examination of the behav-implicated as a major precise nature of its els propose that the atible responses (with
