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Missing data: Our view of the state of the art
 Psychological Methods
, 2002
"... Statistical procedures for missing data have vastly improved, yet misconception and unsound practice still abound. The authors frame the missingdata problem, review methods, offer advice, and raise issues that remain unresolved. They clear up common misunderstandings regarding the missing at random ..."
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Cited by 695 (1 self)
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Statistical procedures for missing data have vastly improved, yet misconception and unsound practice still abound. The authors frame the missingdata problem, review methods, offer advice, and raise issues that remain unresolved. They clear up common misunderstandings regarding the missing at random (MAR) concept. They summarize the evidence against older procedures and, with few exceptions, discourage their use. They present, in both technical and practical language, 2 general approaches that come highly recommended: maximum likelihood (ML) and Bayesian multiple imputation (MI). Newer developments are discussed, including some for dealing with missing data that are not MAR. Although not yet in the mainstream, these procedures may eventually extend the ML and MI methods that currently represent the state of the art. Why do missing data create such difficulty in scientific research? Because most data analysis procedures were not designed for them. Missingness is usually a nuisance, not the main focus of inquiry, but
Multitask Learning
 MACHINE LEARNING
, 1997
"... Multitask Learning is an approach to inductive transfer that improves generalization by using the domain information contained in the training signals of related tasks as an inductive bias. It does this by learning tasks in parallel while using a shared representation; what is learned for each task ..."
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Cited by 660 (6 self)
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Multitask Learning is an approach to inductive transfer that improves generalization by using the domain information contained in the training signals of related tasks as an inductive bias. It does this by learning tasks in parallel while using a shared representation; what is learned for each task can help other tasks be learned better. This paper reviews prior work on MTL, presents new evidence that MTL in backprop nets discovers task relatedness without the need of supervisory signals, and presents new results for MTL with knearest neighbor and kernel regression. In this paper we demonstrate multitask learning in three domains. We explain how multitask learning works, and show that there are many opportunities for multitask learning in real domains. We present an algorithm and results for multitask learning with casebased methods like knearest neighbor and kernel regression, and sketch an algorithm for multitask learning in decision trees. Because multitask learning works, can be applied to many different kinds of domains, and can be used with different learning algorithms, we conjecture there will be many opportunities for its use on realworld problems.
Missing value estimation methods for DNA microarrays
, 2001
"... Motivation: Gene expression microarray experiments can generate data sets with multiple missing expression values. Unfortunately, many algorithms for gene expression analysis require a complete matrix of gene array values as input. For example, methods such as hierarchical clustering and Kmeans clu ..."
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Cited by 470 (24 self)
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Motivation: Gene expression microarray experiments can generate data sets with multiple missing expression values. Unfortunately, many algorithms for gene expression analysis require a complete matrix of gene array values as input. For example, methods such as hierarchical clustering and Kmeans clustering are not robust to missing data, and may lose effectiveness even with a few missing values. Methods for imputing missing data are needed, therefore, to minimize the effect of incomplete data sets on analyses, and to increase the range of data sets to which these algorithms can be applied. In this report, we investigate automated methods for estimating missing data.
Efficient Estimation of Average Treatment Effects Using the Estimated Propensity Score
, 2000
"... We are interested in estimating the average effect of a binary treatment on a scalar outcome. If assignment to the treatment is independent of the potential outcomes given pretreatment variables, biases associated with simple treatmentcontrol average comparisons can be removed by adjusting for diff ..."
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Cited by 393 (34 self)
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We are interested in estimating the average effect of a binary treatment on a scalar outcome. If assignment to the treatment is independent of the potential outcomes given pretreatment variables, biases associated with simple treatmentcontrol average comparisons can be removed by adjusting for differences in the pretreatmentvariables. Rosenbaum and Rubin (1983, 1984) show that adjusting solely for differences between treated and control units in a scalar function of the pretreatment variables, the propensity score, also removes the entire bias associated with differences in pretreatment variables. Thus it is possible to obtain unbiased estimates of the treatment effect without conditioning on a possibly highdimensional vector of pretreatment variables. Although adjusting for the propensity score removes all the bias, this can come at the expense of efficiency. We show that weighting with the inverse of a nonparametric estimate of the propensity score, rather than the true propensity scor...
Where do interorganizational networks come from?
, 1998
"... Organizations enter alliances with each other to access critical resources, but they rely on information from the network of prior alliances to determine with whom to cooperate. These new alliances modify the existing network, prompting an endogenous dynamic between organizational action and network ..."
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Cited by 377 (10 self)
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Organizations enter alliances with each other to access critical resources, but they rely on information from the network of prior alliances to determine with whom to cooperate. These new alliances modify the existing network, prompting an endogenous dynamic between organizational action and network structure that drives the emergence of interorganizational networks. Testing these ideas on alliances formed in three industries over nine years, the authors show that the probability of a new alliance between specific organizations increases with their interdependence, but also with their prior mutual alliances, common third parties, and joint centrality in the alliance network. The differentiation of the emerging network structure, however, mitigates the effect of interdependence and enhances the effect of joint centrality on new alliance formation.
GTM: The generative topographic mapping
 Neural Computation
, 1998
"... Latent variable models represent the probability density of data in a space of several dimensions in terms of a smaller number of latent, or hidden, variables. A familiar example is factor analysis which is based on a linear transformations between the latent space and the data space. In this paper ..."
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Cited by 355 (6 self)
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Latent variable models represent the probability density of data in a space of several dimensions in terms of a smaller number of latent, or hidden, variables. A familiar example is factor analysis which is based on a linear transformations between the latent space and the data space. In this paper we introduce a form of nonlinear latent variable model called the Generative Topographic Mapping for which the parameters of the model can be determined using the EM algorithm. GTM provides a principled alternative to the widely used SelfOrganizing Map (SOM) of Kohonen (1982), and overcomes most of the significant limitations of the SOM. We demonstrate the performance of the GTM algorithm on a toy problem and on simulated data from flow diagnostics for a multiphase oil pipeline. Copyright c○MIT Press (1998). 1
A Unifying Review of Linear Gaussian Models
, 1999
"... Factor analysis, principal component analysis, mixtures of gaussian clusters, vector quantization, Kalman filter models, and hidden Markov models can all be unified as variations of unsupervised learning under a single basic generative model. This is achieved by collecting together disparate observa ..."
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Cited by 345 (18 self)
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Factor analysis, principal component analysis, mixtures of gaussian clusters, vector quantization, Kalman filter models, and hidden Markov models can all be unified as variations of unsupervised learning under a single basic generative model. This is achieved by collecting together disparate observations and derivations made by many previous authors and introducing a new way of linking discrete and continuous state models using a simple nonlinearity. Through the use of other nonlinearities, we show how independent component analysis is also a variation of the same basic generative model. We show that factor analysis and mixtures of gaussians can be implemented in autoencoder neural networks and learned using squared error plus the same regularization term. We introduce a new model for static data, known as sensible principal component analysis, as well as a novel concept of spatially adaptive observation noise. We also review some of the literature involving global and local mixtures of the basic models and provide pseudocode for inference and learning for all the basic models.
Large Sample Properties of Matching Estimators for Average Treatment Effects
 ECONOMETRICA 74,235267
, 2006
"... Matching estimators for average treatment effects are widely used in evaluation research despite the fact that their large sample properties have not been established in many cases. The absence of formal results in this area may be partly due to the fact that standard asymptotic expansions do not ap ..."
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Cited by 308 (17 self)
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Matching estimators for average treatment effects are widely used in evaluation research despite the fact that their large sample properties have not been established in many cases. The absence of formal results in this area may be partly due to the fact that standard asymptotic expansions do not apply to matching estimators with a fixed number of matches because such estimators are highly nonsmooth functionals of the data. In this article we develop new methods for analyzing the large sample properties of matching estimators and establish a number of new results. We focus on matching with replacement with a fixed number of matches. First, we show that matching estimators are not N1/2consistent in general and describe conditions under which matching estimators do attain N1/2consistency. Second, we show that even in settings where matching estimators are N1/2consistent, simple matching estimators with a fixed number of matches do not attain the semiparametric efficiency bound. Third, we provide a consistent estimator for the large sample variance that does not require consistent nonparametric estimation of unknown functions. Software for implementing these methods is available in Matlab, Stata, and R.
Operations for Learning with Graphical Models
 Journal of Artificial Intelligence Research
, 1994
"... This paper is a multidisciplinary review of empirical, statistical learning from a graphical model perspective. Wellknown examples of graphical models include Bayesian networks, directed graphs representing a Markov chain, and undirected networks representing a Markov field. These graphical models ..."
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Cited by 274 (13 self)
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This paper is a multidisciplinary review of empirical, statistical learning from a graphical model perspective. Wellknown examples of graphical models include Bayesian networks, directed graphs representing a Markov chain, and undirected networks representing a Markov field. These graphical models are extended to model data analysis and empirical learning using the notation of plates. Graphical operations for simplifying and manipulating a problem are provided including decomposition, differentiation, and the manipulation of probability models from the exponential family. Two standard algorithm schemas for learning are reviewed in a graphical framework: Gibbs sampling and the expectation maximization algorithm. Using these operations and schemas, some popular algorithms can be synthesized from their graphical specification. This includes versions of linear regression, techniques for feedforward networks, and learning Gaussian and discrete Bayesian networks from data. The paper conclu...
Preliminary Guidelines for Empirical Research in Software Engineering
 IEEE TRANSACTIONS ON SOFTWARE ENGINEERING
, 2002
"... ... propose a preliminary set of research guidelines aimed at stimulating discussion among software researchers. They are based on a review of research guidelines developed for medical researchers and on our own experience in doing and reviewing software engineering research. The guidelines are inte ..."
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Cited by 254 (5 self)
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... propose a preliminary set of research guidelines aimed at stimulating discussion among software researchers. They are based on a review of research guidelines developed for medical researchers and on our own experience in doing and reviewing software engineering research. The guidelines are intended to assist researchers, reviewers, and metaanalysts in designing, conducting, and evaluating empirical studies. Editorial boards of software engineering journals may wish to use our recommendations as a basis for developing guidelines for reviewers and for framing policies for dealing with the design, data collection, and analysis and reporting of empirical studies. Index TermsÐEmpirical software research, research guidelines, statistical mistakes.