We implement and study a computational model of Stevens' [1992] theory of the pathogenesis of schizophrenia. This theory hypothesizes that the onset of schizophrenia is associated with reactive synaptic regeneration occurring in brain regions receiving degenerating temporal lobe projections. Concentrating on one such area, the frontal cortex, we model a frontal module as an associative memory neural network whose input synapses represent incoming temporal projections. Modeling Stevens' hypothesized pathological synaptic changes in this framework results in adverse side effects reminiscent of hallucinations and delusions seen in schizophrenia: spontaneous, stimulusindependent retrieval of stored memories focused on just a few of the stored patterns. These could account for the occurrence of schizophrenic delusions and hallucinations without any apparent external trigger, and for their tendency to concentrate on a few central cognitive and perceptual themes. The model explains why schizo...