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A Review of Molecular Mechanisms of the Anti-Leukemic Effects of Phenolic Compounds in Honey
, 2012
"... Abstract: Hematologic malignancies constitute about 9 % of all new cases of cancers as reported via the GLOBOCAN series by International Agency for Research on Cancer (IARC) in 2008. So far, the conventional therapeutic and surgical approaches to cancer therapy have not been able to curtail the risi ..."
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Abstract: Hematologic malignancies constitute about 9 % of all new cases of cancers as reported via the GLOBOCAN series by International Agency for Research on Cancer (IARC) in 2008. So far, the conventional therapeutic and surgical approaches to cancer therapy have not been able to curtail the rising incidence of cancers, including hematological malignancies, worldwide. The last decade has witnessed great research interest in biological activities of phenolic compounds that include anticancer, anti-oxidation and anti-inflammation, among other things. A large number of anticancer agents combat cancer through cell cycle arrest, induction of apoptosis and differentiation, as well as through inhibition of cell growth and proliferation, or a combination of two or more of these mechanisms. Various phenolic compounds from different sources have been reported to be promising anticancer agents by acting through one of these mechanisms. Honey, which has a long history of human consumption both for medicinal and nutritional uses, contains a variety of phenolic compounds such as flavonoids, phenolic acids, coumarins and tannins. This paper presents a review on the molecular mechanisms of the anti-leukemic activity of various phenolic compounds on cell cycle, cell growth and
1 The Ordovician acritarch genus Coryphidium
"... Abstract: The acritarch genus Coryphidium Vavrdová 1972 is one of the most frequently recorded acritarch taxa in the Ordovician. The original diagnoses, stratigraphical ranges and geographical distribution of all Coryphidium species are critically evaluated in a review of published literature supple ..."
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Abstract: The acritarch genus Coryphidium Vavrdová 1972 is one of the most frequently recorded acritarch taxa in the Ordovician. The original diagnoses, stratigraphical ranges and geographical distribution of all Coryphidium species are critically evaluated in a review of published literature supplemented by studies of material from the British Isles, Belgium, the
Perfluorocyclobutane Aromatic Polyethers. Synthesis and Characterization of New Siloxane-Containing Fluoropolymers†
, 1995
"... ABSTRACT: The synthesis and characterization of siloxane-containing perfluorocyclobutane (PFCB) aromatic polyethers, a new class of fluorosiloxane polymers possessing a well-defined linear structure of alternating disiloxanyl-p-phenylene (cis/trans)-1,2-disubstituted perfluorocyclobutyl ether linkag ..."
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ABSTRACT: The synthesis and characterization of siloxane-containing perfluorocyclobutane (PFCB) aromatic polyethers, a new class of fluorosiloxane polymers possessing a well-defined linear structure of alternating disiloxanyl-p-phenylene (cis/trans)-1,2-disubstituted perfluorocyclobutyl ether linkages with known fluoroolefin end groups, is described. The unexpected formation of an aryl Grignard reagent from 4-[(trifluorovinyl)oxy]bromobenzene (2) allowed for the high-yield synthesis of 4-[(trifluorovinyl)oxy]-phenyldimethylsilane (3) which was dehydrogenatively hydrolyzed in situ and condensed to bis[1,3-[4-[(trifluorovinyl)oxy]phenyl]]-1,1,3,3-tetramethyldisiloxane monomer (4). Thermal cyclopolymerization in the bulk produces poly(1,1,3,3-tetramethyldisiloxanyl-p-phenylene-1-oxaperfluorocyclobutylene-2-oxa-p-phenylene) (5) as a clear, flexible, and thermally stable elastomeric film. Copolymerization of 4 with a trifunctional PFCB monomer gives a toughened thermoset with good thermal stability. Monomers and polymers were characterized by 1H, 13C, and 19F NMR and FTIR spectroscopy. Number-average molecular weights were determined by gel permeation chromatography and, when possible, quantitative 19F NMR end group analysis. Synthesis, characterization, thermal analyses, and current scope of PFCB polymer chemistry are discussed.
PALYNOFACIES INSIGHT INTO PALAEOENVIRONMENTAL
, 2008
"... supergroup and palynofacies insight into ..."
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i ROLES OF IGH INTRONIC ENHANCER E IN CLONAL SELECTION AT THE PRE-B TO IMMATURE B CELL TRANSITION AND IN THE ELIMINATION OF AUTOREACTIVE B
, 2013
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"... This report examines the beginning of the educational experiences of students who leave college before their second year, both those who return to college later (stopouts) and those who do not return (stayouts). The report is based on data from the 1989-90 Beginning Postsecondary Students Longitudin ..."
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This report examines the beginning of the educational experiences of students who leave college before their second year, both those who return to college later (stopouts) and those who do not return (stayouts). The report is based on data from the 1989-90 Beginning Postsecondary Students Longitudinal Study. First-year students in 1989-90 were followed up in 1992 and 1994. Among study highlights are the following: overall, nearly 30 percent of first-year students left before their second year; 64 percent of students who left the 4-year sector returned within five years (stopped out), whereas half of students who left the public 2-year sector stopped out and half stayed out; among stopouts in the 4-year sector 42 percent returned to the same institution, whereas in the public 2-year sector, 57 percent returned to the same institution; and in both sectors, students who stayed out were more likely to be older, to have children, and to work full time. Twenty-four tables and figures present data in sections on: overview of first-year leavers, stopout path from 4-year institutions,
The Poetics, Politics and Writing of Memory
, 2015
"... ePublications@SCU is an electronic repository administered by Southern Cross University Library. Its goal is to capture and preserve the intellectual output of Southern Cross University authors and researchers, and to increase visibility and impact through open access to researchers around the world ..."
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ePublications@SCU is an electronic repository administered by Southern Cross University Library. Its goal is to capture and preserve the intellectual output of Southern Cross University authors and researchers, and to increase visibility and impact through open access to researchers around the world. For further information please contact
Mazuelloids: Product of Post-Mortem Phosphatization of
"... Enigmatic microfossils from the early Silurian of Poland known as mazuelloids (5 muellerisphaerids) have been identified as Baltisphaeridium-like acanthomorphic acri-tarchs that have been subject to post-mortem phosphatiza-tion. These acritarchs were the dominant components of large post-bloom macro ..."
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Enigmatic microfossils from the early Silurian of Poland known as mazuelloids (5 muellerisphaerids) have been identified as Baltisphaeridium-like acanthomorphic acri-tarchs that have been subject to post-mortem phosphatiza-tion. These acritarchs were the dominant components of large post-bloom macroaggregates that probably sank rap-idly to the seafloor and were then overgrown by benthic coc-coid cyanobacterial mats. Early diagenetic phosphatization of the remains probably occurred following shallow burial and in proximity to decomposing phosphate-rich macroag-gregates. Depending on phosphate availability, the result-ing phosphate layers were thin or thick and were deposited on the outside, inside, or enveloping the acritarch organic walls from both sides. The unusually large size of the ma-zuelloid-forming acritarchs was probably the result of peri-odically hypertrophic conditions driven by large blooms generated by upwelling currents.
