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...dativesdamage to DNA. Thesactivation of the polyolspathway may be prevented by SFNsdecreasing the cellular concentration ofsmethylglyoxal and thereby preventingsmethylglyoxal-induced expression of ARs=-=(52)-=-.sThese findings provide the biochemicalsbasis for the link of a vegetable-rich diet withsdecreased endothelial dysfunction (53) –sincluding that part of the Mediterranean diets(54), suggestingsdietar...

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...ls and MG-related advanced glycation endproducts have beensreported in different insulin resistance states, which is associated with various clinicalsmanifestations such as hypertension and diabetes (=-=Chang et al., 2002-=-; McLellan et al.,s1994; Riboulet-Chavey et al., 2006; Wang et al., 2004). As one of the major factors ofsinsulin resistance, the correlation between endogenous MG accumulation and thesdevelopment of ...