Results 1 -
3 of
3
Review Insights into Chemoresistance of Prostate Cancer
"... © 2015 Ivyspring International Publisher. Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited. See ..."
Abstract
- Add to MetaCart
(Show Context)
© 2015 Ivyspring International Publisher. Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited. See
Editorial Biological and Clinical Significance of Androgens and Androgen Receptor in Prostate Cancer
"... This special issue provides an update on differ-ent biological and clinical aspects of adrenal andro-gens, androgen biosynthetic pathways, AR-signaling, inter-racial differences in AR mutations, and clinical success and failure of antiandrogens and anti-AR therapies in prostate cancer (PCa). Androge ..."
Abstract
- Add to MetaCart
(Show Context)
This special issue provides an update on differ-ent biological and clinical aspects of adrenal andro-gens, androgen biosynthetic pathways, AR-signaling, inter-racial differences in AR mutations, and clinical success and failure of antiandrogens and anti-AR therapies in prostate cancer (PCa). Androgen receptor (AR), a nuclear steroid receptor and transcription factor, has a central role in the normal growth and development of the prostate gland, in prostate car-cinogenesis, and in the castrate-resistant (CR) pro-gression of PCa [1]. Understanding the critical mo-lecular events that lead PCa cells to resist antiandro-gens or anti-AR therapies is essential in developing successful treatments for CR or advanced stages of the disease [2, 3]. In a relatively significant number of PCa
RESEARCH ARTICLE Open Access The
"... androgen receptor plays a suppressive role in epithelial- mesenchymal transition of human prostate cancer stem progenitor cells ..."
Abstract
- Add to MetaCart
(Show Context)
androgen receptor plays a suppressive role in epithelial- mesenchymal transition of human prostate cancer stem progenitor cells