Registration is a fundamental task in image processing used to match two or more pictures taken, for example, at different times, from different sensors or from different viewpoints. Over the years, a broad range of techniques have been developed for the various types of data and problems. These techniques have been independently studied for several different applications resulting in a large body of research. This paper organizes this material by establishing the relationship between the distortions in the image and the type of registration techniques which are most suitable. Two major types of distortions are distinguished. The first type are those which are the source of misregistration, i.e., they are the cause of the misalignment between the two images. Distortions which are the source of misregistration determine the transformation class which will optimally align the two images. The transformation class in turn influences the general technique that should be taken....

Introduction The ever expanding gamut of medical imaging techniques provides the clinician an increasingly multifaceted view of brain function and anatomy. The information provided by the various imaging modalities is often complementary (i.e. provides separate but useful information) and synergistic (i.e. the combination of information provides useful extra information). For example, X-ray computed tomography (CT) and magnetic resonance (MR) imaging exquisitely demonstrate brain anatomy but provide little functional information. Positron emission tomography (PET) and single photon emission computed tomography (SPECT) scans display aspects of brain function and allow metabolic measurements but poorly delineate anatomy. Furthermore, CT and MR images describe complementary morphologic features. For example, bone and calcifications are best seen on CT images, while soft-tissue structures are better differentiated by MR imaging. Clinical diagnosis and therapy planning and evaluatio

Abstract — The registration of retinal images is required to facilitate the study of the optic nerve head and the retina. The method we propose combines the use of mutual information as the similarity measure and simulated annealing as the search technique. It is robust toward large transformations between the images and significant changes in light intensity. By using a pyramid sampling approach combined with simulated reannealing we find that registration can be achieved to predetermined precision, subject to choice of interpolation and the constraint of time. The algorithm was tested on 49 pairs of stereo images and 48 pairs of temporal images with success. Index Terms—Hierarchical systems, image registration, information theory, simulated annealing, visual system.

Guidance systems designed for neurosurgery, hip surgery, spine surgery, and for approaches to other anatomy that is relatively rigid can use rigid-body transformations to accomplish image registration. These systems often rely on point-based registration to determine the transformation, and many such systems use attached fiducial markers to establish accurate fiducial points for the registration, the points being established by some fiducial localization process. Accuracy is important to these systems, as is knowledge of the level of that accuracy. An advantage of marker-based systems, particularly those in which the markers are bone-implanted, is that registration error depends only on the fiducial localization error (FLE) and is thus to a large extent independent of the particular object being registered. Thus, it should be possible to predict the clinical accuracy of marker-based systems on the basis of experimental measurements made with phantoms or previous patients. This paper pr...

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