• Documents
  • Authors
  • Tables
  • Log in
  • Sign up
  • MetaCart
  • DMCA
  • Donate

CiteSeerX logo

Advanced Search Include Citations

Tools

Sorted by:
Try your query at:
Semantic Scholar Scholar Academic
Google Bing DBLP
Results 1 - 10 of 48
Next 10 →

Efficacy and mechanism of nasal irrigation with a hand pump against influenza and non-Influenza viral upper respiratory tract infection

by Huafei Ao , Qin Wang , Baofa Jiang , Peter He
"... To investigate if nasal irrigation could impact the severity and duration of viral URTI. 22 patients with new ..."
Abstract - Add to MetaCart
To investigate if nasal irrigation could impact the severity and duration of viral URTI. 22 patients with new

High-performance genetically targetable optical neural silencing by light-driven proton pumps. Nature 463

by Brian Y. Chow, Xue Han, Allison S. Dobry, Xiaofeng Qian, Amy S. Chuong, Mingjie Li, Michael A. Henninger, Gabriel M. Belfort, Yingxi Lin, Patrick E, Edward S. Boyden , 2010
"... The ability to silence the activity of genetically specified neurons in a temporally precise fashion would open up the ability to investigate the causal role of specific cell classes in neural computations, behaviors, and pathologies. Here we show that members of the class of light-driven outward pr ..."
Abstract - Cited by 36 (1 self) - Add to MetaCart
proton pumps can mediate very powerful, safe, multiple-color silencing of neural activity. The gene archaerhodopsin-31 (Arch) from Halorubrum sodomense enables near-100 % silencing of neurons in the awake brain when virally expressed in mouse cortex and illuminated with yellow light. Arch mediates

Viral capsid mobility: a dynamic conduit for inactivation

by Klas Broo , Jing Wei , Dawn Marshall , Fred Brown , Thomas J Smith , John E Johnson , Anette Schneemann , Gary Siuzdak , K Barry Sharpless - Proc. Natl. Acad. Sci. USA 98:2274–2277 , 2001
"... Mass spectrometry and fluorescent probes have provided direct evidence that alkylating agents permeate the protein capsid of naked viruses and chemically inactivate the nucleic acid. N-acetylaziridine and a fluorescent alkylating agent, dansyl sulfonate aziridine, inactivated three different viruse ..."
Abstract - Cited by 9 (4 self) - Add to MetaCart
microscopy and sucrose gradient experiments), it was reasoned that the dynamic nature of the viral capsid acts as a conduit to the interior of the particle. Potential applications include fluorescent labeling for imaging viral genomes in living cells, the sterilization of blood products, vaccine development

Correspondence

by Maria Cristina Bonza, Holger Martin, Ming Kang, Gentry Lewis, Timo Greiner, Sonia Giacometti, James L. Van Etten, Maria Ida De, Gerhard Thiel, Anna Moroni, Anna Moroni , 2010
"... Calcium-transporting ATPases (Ca 2+ pumps) are major players in maintaining calcium homeostasis in the cell and have been detected in all cellular organisms. Here, we report the identification of two putative Ca 2+ pumps, M535L and C785L, encoded by chlorella viruses MT325 and AR158, respectively, a ..."
Abstract - Add to MetaCart
, and the functional characterization of M535L. Phylogenetic and sequence analyses place the viral proteins in group IIB of P-type ATPases even though they lack a typical feature of this class, a calmodulin-binding domain. A Ca 2+ pump gene is present in 45 of 47 viruses tested and is transcribed during virus

Multiple-color optical activation, silencing, and desynchronization of neural activity, with single-spike temporal resolution

by Xue Han, Edward S. Boyden - PLoS ONE , 2007
"... The quest to determine how precise neural activity patterns mediate computation, behavior, and pathology would be greatly aided by a set of tools for reliably activating and inactivating genetically targeted neurons, in a temporally precise and rapidly reversible fashion. Having earlier adapted a li ..."
Abstract - Cited by 76 (12 self) - Add to MetaCart
-driven chloride pump halorhodopsin from the archaebacterium Natronomas pharaonis (hereafter abbreviated Halo) to genetically-specified neurons enables them to be silenced reliably, and reversibly, by millisecond-timescale pulses of yellow light. We show that trains of yellow and blue light pulses can drive high

Convergent radial tracing of viral and solute transport in gneiss saprolite

by Richard Taylor, Callist Tindimugaya, John Barker, David Macdonald, Robinah Kulabako - Ground Water , 2010
"... Deeply weathered crystalline rock aquifer systems comprising unconsolidated saprolite and underlying frac-tured bedrock (saprock) underlie 40 % of sub-Saharan Africa. The vulnerability of this aquifer system to contami-nation, particularly in rapidly urbanizing areas, remains poorly understood. In o ..."
Abstract - Cited by 6 (3 self) - Add to MetaCart
. In order to assess solute and viral transport in saprolite derived from Precambrian gneiss, forced-gradient tracer experiments using chloride and Es-cherichia coli phage FX174 were conducted in southeastern Uganda. The bacteriophage tracer was largely unre-covered; adsorption to the weathered crystalline

Comparison of a Constitutive Viral Versus an Endothelin-1–Responsive Cardiac Promoter

by Contractile Dysfunction, Karin Eizema, Phd Henry Fechner, Dvm Karel Bezstarosti, Bsc Sonja Schneider-rasp, Arnoud Van Der Laarse, Phd Haili Wang, Md Heinz-peter Schultheiss, Wolfgang C. Poller, Md Jos, M. J. Lamers
"... Background—A decrease in sarcoplasmic reticulum Ca21 pump (SERCA2) activity is believed to play a role in the impairment of diastolic function of the failing heart. Because the expression ratio of phospholamban (PL) to SERCA2 may be a target to improve contractile dysfunction, a PL antisense RNA str ..."
Abstract - Add to MetaCart
Background—A decrease in sarcoplasmic reticulum Ca21 pump (SERCA2) activity is believed to play a role in the impairment of diastolic function of the failing heart. Because the expression ratio of phospholamban (PL) to SERCA2 may be a target to improve contractile dysfunction, a PL antisense RNA

LETTERS High-performance genetically targetable optical neural silencing by light-driven proton pumps

by Brian Y. Chow, Xue Han, Allison S. Dobry, Xiaofeng Qian, Amy S. Chuong, Mingjie Li, Michael A. Henninger, Gabriel M. Belfort, Yingxi Lin, Patrick E. Monahan, Edward S. Boyden
"... The ability to silence the activity of genetically specified neurons in a temporally precise fashion would provide the opportunity to investigate the causal role of specific cell classes in neural compu-tations, behaviours and pathologies. Here we show that members of the class of light-driven outwa ..."
Abstract - Add to MetaCart
-driven outward proton pumps can mediate powerful, safe, multiple-colour silencing of neural activity. The gene archaerhodopsin-3 (Arch)1 from Halorubrum sodomense enables near-100 % silencing of neurons in the awake brain when virally expressed in the mouse cortex and illuminated with yellow light. Arch mediates

Post-Weaning Breast Milk HIV-1 Viral Load, Blood Prolactin Levels and Breast Milk Volume

by Donald M. Theaa, Grace Aldrov, Chipepo Kankasac, Prisca Kasondec, W. Donald, Katherine Semraua, Moses Sinkalad, Louise Kuhne
"... Background: The effect of abrupt weaning, advocated as a safe transition from exclusive breastfeeding in HIV-exposed children, on the quantity of HIV viral load in breast milk (BMVL) is not known. Objectives: To determine the effect of abrupt cessation of breastfeeding on serum prolactin, pumped bre ..."
Abstract - Add to MetaCart
Background: The effect of abrupt weaning, advocated as a safe transition from exclusive breastfeeding in HIV-exposed children, on the quantity of HIV viral load in breast milk (BMVL) is not known. Objectives: To determine the effect of abrupt cessation of breastfeeding on serum prolactin, pumped

Comparative genomics of the FtsK–HerA

by Lakshminarayan M. Iyer, Kira S. Makarova, Eugene V. Koonin, L. Aravind , 2004
"... superfamily of pumping ATPases: implications for the origins of chromosome segregation, cell division and viral capsid packaging ..."
Abstract - Add to MetaCart
superfamily of pumping ATPases: implications for the origins of chromosome segregation, cell division and viral capsid packaging
Next 10 →
Results 1 - 10 of 48
Powered by: Apache Solr
  • About CiteSeerX
  • Submit and Index Documents
  • Privacy Policy
  • Help
  • Data
  • Source
  • Contact Us

Developed at and hosted by The College of Information Sciences and Technology

© 2007-2019 The Pennsylvania State University