. The methodology is founded on the view of a system as a computational organisation consisting of various interacting roles. We illustrate the methodology through a case study (an agent-based business process management system).

agents in context, defines them and then goes on, inter alia, to overview critically the rationales, hypotheses, goals, challenges and state-of-the-art demonstrators of the various agent types in our typology. Hence, it attempts to make explicit much of what is usually implicit in the agents literature

This paper develops a theory of the allocation of formal authority (the right to decide) and real authority (the effective control over decisions) within organizations, and it illustrates how a formally integrated structure can accommodate various degrees of "real" integration. Real

. This allows programs to reason about the state of the world and consider the effects of various possible courses of action before committing to a particular behavior. The net effect is that programs may be written at a much higher level of abstraction than is usually possible. The language appears well suited

types of therapeutically induced tumour regression. It is implicated in both physiological involution and atrophy of various tissues and organs. It can also be triggered by noxious agents, both in the embryo and adult animal. IN recent years it has become widely recognized that spontaneous loss of cells

By comparing phosphorus loss from enamel windows during successive exposures in acetic acid buffer, measurements were made of the effects of a number of uncommon fluoride and nonfluoride compounds on enamel dissolution. Acidulated ytterbium chloride and the tetrafluorides of titanium, zirconium, and hafnium gave much more lasting protection against the action of acid than did the fluorides commonly used for caries prophylaxis. Since the initial demonstration that sodium fluoride reduced the solubility of dental enamel ' and that its application to the teeth prevented caries,2 several investigators

We explore the notion of a tour guide software agent for assisting users browsing the World Wide Web. A Web tour guide agent provides assistance similar to that provided by ahuman tour guide in a museum -- it guides the user along an appropriate path through the collection, based on its knowledge

. We introduce a calculus for mobile agents and give its chemical semantics, with a precise definition for migration, failure, and failure detection. Various examples written in our calculus illustrate how to express remote executions, dynamic loading of remote resources and protocols with mobile

The promoting activities of 29 compounds on induction of hyperplastic (neoplastic) liver nodules (HN) and the dose-dependent effects of tumor promoting agents were compared by using a shortterm test system developed in this laboratory. In tests on promoting activity, F344 rats were given a single

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