INTRODUCTION A logo is "a single piece of type bearing two or more usually separate elements" [1]. In this paper, we use logos to display aligned sets of sequences. Sequence logos concentrate the following information into a single graphic [2]: 1. The general consensus of the sequences

Context is a poorly used source of information in our computing environments. As a result, we have an impoverished understanding of what context is and how it can be used. In this paper, we provide an operational definition of context and discuss the different ways that context can be used

Recent work in Artificial Intelligence is exploring the use of formal ontologies as a way of specifying content-specific agreements for the sharing and reuse of knowledge among software entities. We take an engineering perspective on the development of such ontologies. Formal ontologies are viewed

Currently, most approaches to retrieving textual materials from scientific databases depend on a lexical match between words in users' requests and those in or assigned to documents in a database. Because of the tremendous diversity in the words people use to describe the same document

scales. In this paper we suggest a new definition of scale-space, and introduce a class of algorithms that realize it using a diffusion process. The diffusion coefficient is chosen to vary spatially in such a way as to encourage intraregion smoothing in preference to interregion smoothing. It is shown

of the target gene relative to some reference group The two most commonly used methods to analyze data from real-time, quantitative PCR experiments are absolute quantifica-such as an untreated control or a sample at time zero tion and relative quantification. Absolute quantification deter- in a

these features in an optimal way, we train a classifier using human labeled images as ground truth. The output of this classifier provides the posterior probability of a boundary at each image location and orientation. We present precision-recall curves showing that the resulting detector significantly

The large-scale automated transaction systems of the near future can be designed to protect the privacy and maintain the security of both individuals and organizations. DAVID CHAUM Computerization is robbing individuals of the ability to monitor and control the ways information about them is used

is easy for programmers to use. The subtype relation is based on the specifications of the sub- and supertypes; the paper presents a way of specifying types that makes it convenient to define the subtype relation. The paper also discusses the ramifications of this notion of subtyping on the design of type

For manytypes of learners one can compute the statistically "optimal" way to select data. We review how these techniques have been used with feedforward neural networks [MacKay, 1992# Cohn, 1994]. We then showhow the same principles may be used to select data for two alternative