This article was republished on May 13, 2015, because radical signs used to differentiate native and radical forms of species were omitted throughout the paper. These errors were introduced during the typesetting process. The publisher apologizes for these errors. The originally pub-lished, uncorrected article and the republished, corrected article are provided here for reference. Supporting Information S1 File. Originally published, uncorrected article.

xanthine to uric acid by xanthine oxidase, superoxide anion and hydrogen peroxide are produced along with the hydroxyl radical. Our studies demonstrate that washed human platelets incubated with xanthine and xanthine oxidase aggregated and released [14C]-serotonin. Aggregation and release were

anion radical, 02.-, in the reaction. Up to pH 9.1 the reaction is still inhibited to over 90 % by superoxide dismutase, but at higher alkalinity, O,.--independent mechanisms rapidly become dominant. Catalase has no effect on the autoxidation but decreases the oxygen consumption by half, showing that H

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generate superoxide anion (02-), a free radical of oxy-gen, and a possible role for this radical or its deriva-tives in the killing of phagocytized bacteria were ex-plored using leukocytes from normal individuals and patients with chronic granulomatous disease (CGD). Superoxide dismutase, which

AIM: To investigate the ability of ursodeoxycholic acid (UDCA) to scavenge superoxide anion (O2–). METHODS: We assessed the ability of UDCA to scavenge (O2–) generated by xanthine-xanthine oxidase (X-XO) in a cell-free system and its effect on the rate of O2–-induced ascorbic acid (AA) oxidation

Abstract—Oxygen free radicals are believed to play a key role in cellular proliferation, and increased concentrations of these molecules have been implicated in the pathogenesis of endothelial dysfunction in diabetes mellitus. Our aim was to study the role of superoxide anions in endothelial cell

that H. somnus significantly (P <0.001) inhibited production of superoxide anion (O2-) by bovine mammary and alveolar macrophages as well as by polymorphonuclear leukocytes. Inhibition of O2- production was time- and dose-dependent and did not occur after incubation with Escherichia coli, H