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Results 11 - 20
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8,248
Aging: a theory based on free radical and radiation chemistry
- J Gerontol
, 1956
"... The phenomenon of growth, decline and death-aging-has been the source of consider-able speculation (1, 8, 10). This cycle seems to be a more or less direct function of the meta-bolic rate and this in turn depends on the species (animal or plant) on which are super-imposed the factors of heredity and ..."
Abstract
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Cited by 637 (2 self)
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and the effects of the stresses and strains of life-which alter the metabolic activity. The universality of this phenomenon sug-gests that the reactions which cause it are basic-ally the same in all living things. Viewing this process in the light of present day free radical and radiation chemistry
Protein kinases
"... doi:10.1093/cvr/cvm017 Shear stress-induced activation of the AMP-activated protein kinase regulates FoxO1a and angiopoietin-2 in endothelial cells ..."
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doi:10.1093/cvr/cvm017 Shear stress-induced activation of the AMP-activated protein kinase regulates FoxO1a and angiopoietin-2 in endothelial cells
the review on
- D0 −D0 Mixing” in this Review
"... Abstract Recurrent spontaneous abortion (RSA) is de-fined as three or more consecutive pregnancy losses prior to the 20th week of gestation. The etiology of recurrent spontaneous abortion is often unclear and may be multifactorial, with much controversy regarding diag-nosis and treatment. Reasonably ..."
Abstract
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Cited by 361 (4 self)
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-Bf) antibodies that may play major role in the immunologic failure of pregnancy and may lead to abortion. Alter-ation in the expression of HLA-G molecules, T-helper-1 (Th-1) pattern of cytokines and natural killer (NK) cells activity may also induce abortion. Various forms of treatment like antithrombotic
Stress-induced changes in the electrical conductivity of igneous rocks and the generation of ground currents
- Terr. Atmos. Ocean Sci
"... If we can ever hope to understand the non-seismic signals that the Earth sends out before major earthquakes, we need to understand the physics of rocks under increased levels of stress. In particular we need to understand the generation of electrical currents in the ground. We have begun to study ho ..."
Abstract
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Cited by 4 (3 self)
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posit that stress-induced activation of p-hole charge carriers and their outflow from the source volume is the basic process by which
Endoplasmic Reticulum Stress Activates the Hepatic Activator Protein 1 Complex via Mitogen Activated Protein Kinase-Dependent Signaling Pathways
"... Background and Aims: Endoplasmic reticulum (ER) stress is induced in many forms of chronic liver disease and may promote the development of hepatocellular carcinoma. The activator protein 1 (AP-1) complex is a transcription factor that promotes hepatic carcinogenesis in response to cellular stress. ..."
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the role of MAPK signaling in ER stress-induced AP-1 activation, ER stress was induced in JNK- and ERK-inhibited HepG2 cells. Results: Induction of ER stress promoted the activation of both Jun- and Fos-related genes and proteins of the AP-1 complex in HepG2 cells and murine liver. Inhibition of ERK
BLOOD FIBRINOLYTIC ACTIVITY DURING MAJOR SURGERY IN UNSUPPLEMENTED GLUCOCORTICOID-TREATED PATIENTS
"... Blood clot lysis time (BLT) and plasma cortisol concentration were measured during major abdominal surgery in 15 unsupplemented glucocorticoid-treated patients. Eight patients showed an impaired cortisol response and seven patients had normal cortisol concentrations when compared with the cortisol r ..."
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response of 23 control patients with normal pituitary-adrenal function. There was no statistically significant difference between variations of BLT in the group of patients with impaired cortisol response and patients with normal cortisol concentrations. It is concluded that stress-induced activation
Rho-stimulated contractility drives the formation of stress fibers and focal adhesions
- J. Cell Biol
, 1996
"... Abstract. Activated rhoA, a ras-related GTP-binding protein, stimulates the appearance of stress fibers, focal adhesions, and tyrosine phosphorylation in quiescent cells (Ridley, A.J., and A. Hall, 1992. Cell. 70:389-399). The pathway by which rho triggers these events has not been elucidated. Many ..."
Abstract
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Cited by 309 (5 self)
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. We demonstrate that stimulation of fibroblasts with lysophosphatidic acid, which activates rho, induces myosin light chain phosphorylation. This precedes the forma-tion of stress fibers and focal adhesions and is accompanied by increased contractility. Inhibition of contractility by several different
Stress-Induced Sickness
, 2000
"... ABSTRACT: During maternal separation, some primate and nonprimate species show a biphasic (active/passive) response. The second stage is characterized by reduced activity, a hunched body posture, and other behaviors. Traditionally, the second stage has been referred to as ``despair' ' and ..."
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; and is considered an animal model for human depression. Recent research in psychoneuroimmunology suggests an alternative hypothesisÐthat behaviors occurring during the second passive phase represent stress-induced ``sickness behaviors.' ' This perspective more readily accounts for ®ndings in widely
Effect of ‘‘Rose Essential Oil’ ’ Inhalation on Stress-Induced Skin-Barrier Disruption in Rats and Humans
, 2011
"... In stressed animals, several brain regions (e.g., hypothalamic paraventricular nucleus [PVN]) exhibit neuronal activation, which increases plasma adrenocorticotropic hormone (ACTH) and glucocorticoids. We previously reported that so-called ‘‘green odor’’ inhibits stress-induced activation of the hyp ..."
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In stressed animals, several brain regions (e.g., hypothalamic paraventricular nucleus [PVN]) exhibit neuronal activation, which increases plasma adrenocorticotropic hormone (ACTH) and glucocorticoids. We previously reported that so-called ‘‘green odor’’ inhibits stress-induced activation
Results 11 - 20
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8,248
