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Results 1 - 10
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7,043
Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics
- Mol. Cell. Proteomics
, 2002
"... The abbreviations used are: SILAC: Stable isotope labeling by amino acids in cell culture, 2DE: two dimensional (isoelectric focusing/SDS-PAGE) gel electrophoresis: ICATTM: isotope-coded affinity tag; MS: mass spectrometry; MALDI-TOF: matrix assisted laser desorption ionization-time of flight; PMF: ..."
Abstract
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Cited by 595 (23 self)
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: peptide mass fingerprinting; LC-MS: liquid chromatography-MS; Copyright 2002 by The American Society for Biochemistry and Molecular Biology, Inc. Quantitative proteomics has traditionally been performed by 2D gel electrophoresis but recently, mass spectrometric methods based on stable isotope quantitation
Estimating evaporation using stable isotopes: quantitative results and sensitivity analysis for two catchrnents in northern Canada. Nordic Hydrology 24: 79
, 1993
"... The stable isotope-mass balance method can provide useful water balance information in ungauged catchments. The method has been used to evaluate evaporation and water balance at two contrasting sites in northern Canada. Areally weighted evaporative discharge from an 850 km2 tundra catchment in south ..."
Abstract
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Cited by 14 (6 self)
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The stable isotope-mass balance method can provide useful water balance information in ungauged catchments. The method has been used to evaluate evaporation and water balance at two contrasting sites in northern Canada. Areally weighted evaporative discharge from an 850 km2 tundra catchment
Curvelets: a surprisingly effective nonadaptive representation of objects with edges
- IN CURVE AND SURFACE FITTING: SAINT-MALO
, 2000
"... It is widely believed that to efficiently represent an otherwise smooth object with discontinuities along edges, one must use an adaptive representation that in some sense ‘tracks ’ the shape of the discontinuity set. This folk-belief — some would say folk-theorem — is incorrect. At the very least ..."
Abstract
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Cited by 395 (21 self)
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least, the possible quantitative advantage of such adaptation is vastly smaller than commonly believed. We have recently constructed a tight frame of curvelets which provides stable, efficient, and near-optimal representation of otherwise smooth objects having discontinuities along smooth curves
Multiplexed protein quantitation in Saccharomyces cerevisiae using aminereactive isobaric tagging reagents,”
- Molecular and Cellular Proteomics,
, 2004
"... We describe here a multiplexed protein quantitation strategy that provides relative and absolute measurements of proteins in complex mixtures. At the core of this methodology is a multiplexed set of isobaric reagents that yield amine-derivatized peptides. The derivatized peptides are indistinguisha ..."
Abstract
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Cited by 248 (1 self)
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utilizing MS and a host of stable isotope-labeling chemistries have emerged (reviewed in Refs. 1 and 2), offering a departure from traditional techniques employing comparative two-dimensional gel electrophoresis. The ICAT quantitative labeling strategy (3, 4) is perhaps the best-characterized method
Quantitative universality for a class of nonlinear Transformations
- J. Statistical Physics
, 1978
"... A large class of recursion relations xn+l = Af(xn) exhibiting infinite bifurcation is shown to possess a rich quantitative structure essentially independent of the recursion function. The functions considered all have a unique differentiable maximum 2. With f(2)- f(x) ~ Ix- 21 " (for Ix- 21 su ..."
Abstract
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Cited by 263 (0 self)
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A large class of recursion relations xn+l = Af(xn) exhibiting infinite bifurcation is shown to possess a rich quantitative structure essentially independent of the recursion function. The functions considered all have a unique differentiable maximum 2. With f(2)- f(x) ~ Ix- 21 " (for Ix- 21
Stable isotope‐based paleoaltimetry,
- Ann. Rev. Earth Planet. Sci.,
, 2007
"... Abstract The quantitative estimation of paleoaltitude has become an increasing focus of Earth scientists because surface elevation provides constraints on the geodynamic mechanisms operating in mountain belts, as well as the influence of mountain belt growth on regional and global climate. The gene ..."
Abstract
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Cited by 15 (0 self)
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the elevation at the time the minerals were forming. In this review we provide a theory behind the application of stable isotope-based approaches to paleoaltimetry. We apply this theory to test cases using modern precipitation and surface water isotopic compositions to demonstrate that it generally accords well
Research Stable Isotope Labeling by Amino Acids in Cell Culture, SILAC, as a Simple and Accurate Approach to Expression Proteomics*
"... Quantitative proteomics has traditionally been performed by two-dimensional gel electrophoresis, but recently, mass spectrometric methods based on stable isotope quantitation have shown great promise for the simultaneous and automated identification and quantitation of complex protein mixtures. Here ..."
Abstract
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Quantitative proteomics has traditionally been performed by two-dimensional gel electrophoresis, but recently, mass spectrometric methods based on stable isotope quantitation have shown great promise for the simultaneous and automated identification and quantitation of complex protein mixtures
Quantitative, Multiplexed Assays for Low Abundance Proteins in Plasma by Targeted Mass Spectrometry and Stable Isotope Dilution * □S
"... Biomarker discovery produces lists of candidate markers whose presence and level must be subsequently verified in serum or plasma. Verification represents a paradigm shift from unbiased discovery approaches to targeted, hypothesis-driven methods and relies upon specific, quantitative assays optimize ..."
Abstract
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Cited by 58 (3 self)
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optimized for the selective detection of target proteins. Many protein biomarkers of clinical currency are present at or below the nanogram/milliliter range in plasma and have been inaccessible to date by MS-based methods. Using multiple reaction monitoring coupled with stable isotope dilution mass
Mass spectrometric quantitation of peptides and proteins using Stable Isotope Standards and Capture by Anti-Peptide Antibodies
"... A method (denoted SISCAPA) for quantitation of peptides in complex digests is described. In the method, anti-peptide antibodies immobilized on 100 nanoliter nanoaffinity columns are used to enrich specific peptides along with spiked stable-isotope-labeled internal standards of the same sequence. Upo ..."
Abstract
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Cited by 54 (4 self)
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A method (denoted SISCAPA) for quantitation of peptides in complex digests is described. In the method, anti-peptide antibodies immobilized on 100 nanoliter nanoaffinity columns are used to enrich specific peptides along with spiked stable-isotope-labeled internal standards of the same sequence
Palaeo-climate reconstruction from stable isotope variations in speleothems: a review
- Quaternary Science Reviews
, 2004
"... Speleothems are now regarded as valuable archives of climatic conditions on the continents, offering a number of advantages relative to other continental climate proxy recorders such as lake sediments and peat cores. They are ideal materials for precise U-series dating, yielding ages in calendar yea ..."
Abstract
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Cited by 60 (2 self)
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years, thereby circumventing the radiocarbon calibration problems associated with most other continental records. Stable isotope studies in speleothems have shifted away from attempting to provide palaeo-temperature reconstructions to the attainable goal of providing precise estimates for the timing
Results 1 - 10
of
7,043
