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335
Review Article: An approach to mild to moderate atopic eczema
"... The aetiology of atopic eczema encompasses a complex interplay between genetic factors, disrupted skin barrier function, food allergy and many other extrinsic factors.1 Clinically, it affects the entire body of infants, the extensor ..."
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The aetiology of atopic eczema encompasses a complex interplay between genetic factors, disrupted skin barrier function, food allergy and many other extrinsic factors.1 Clinically, it affects the entire body of infants, the extensor
Effect of ‘‘Rose Essential Oil’ ’ Inhalation on Stress-Induced Skin-Barrier Disruption in Rats and Humans
, 2011
"... In stressed animals, several brain regions (e.g., hypothalamic paraventricular nucleus [PVN]) exhibit neuronal activation, which increases plasma adrenocorticotropic hormone (ACTH) and glucocorticoids. We previously reported that so-called ‘‘green odor’’ inhibits stress-induced activation of the hyp ..."
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-Fos-positive cells in PVN. Inhalation of rose essential oil significantly inhibited the following effects of chronic stress: 1) the elevation of transepidermal water loss (TEWL), an index of the disruption of skin-barrier function, in both rats and humans and 2) the increase in the salivary concentration of cortisol
‘‘Green Odor’ ’ Inhalation Reduces the Skin-Barrier Disruption Induced by Chronic Restraint Stress in Rats: Physiological and Histological Examinations
"... We investigated whether inhalation of green odor (a mixture of equal amounts of trans-2-hexenal and cis-3-hexenol) prevents the skin-barrier disruption induced by chronic restraint stress in rats. To this end, transepidermal water loss (TEWL) was measured as an index of the disruption of skin-barrie ..."
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We investigated whether inhalation of green odor (a mixture of equal amounts of trans-2-hexenal and cis-3-hexenol) prevents the skin-barrier disruption induced by chronic restraint stress in rats. To this end, transepidermal water loss (TEWL) was measured as an index of the disruption of skin-barrier
© Copyright The Korean Academy of Asthma, Allergy and Clinical Immunology • The Korean Academy of Pediatric Allergy and Respiratory Disease http://e-aair.org 79
"... Atopic dermatitis (AD) is a chronic relapsing pruritic inflam-matory skin disease. AD is characterized by abnormalities in skin barrier function, allergen sensitization, and recurrent skin infections. Since the 1960s the prevalence of AD has increased ..."
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Atopic dermatitis (AD) is a chronic relapsing pruritic inflam-matory skin disease. AD is characterized by abnormalities in skin barrier function, allergen sensitization, and recurrent skin infections. Since the 1960s the prevalence of AD has increased
Atopic dermatitis: Therapeutic
, 2008
"... b mice lacking serine protease inhibitor Kazal type 5 (SPINK5), the gene deficient in Netherton syndrome and encoding the serine protease inhibitor lymphoepithelial Kazal type inhibitor (LEKTI), exhibit substantial barrier dysfunctions through uncon-trolled epidermal serine protease activity.9 Conco ..."
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Concordant with this is the observation that epidermal overexpression of mouse kalli-krein 7, a serine protease under the control of LEKTI, mediates skin barrier function.10 Finally, mice with transgenic expression of human apolipoprotein C1 in the liver and skin display a dis-turbed skin barrier function
SpecIaL FOcuS ReVIew SpecIaL FOcuS ReVIew
"... HDM allergy is the most prevalent indoor sensitization. It is associated with atopic dermatitis, perennial rhinitis and asthma. Chronic atopic dermatitis, which afflicts 2 % of people,1 results from reduced skin barrier function, often caused by mutation of ..."
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HDM allergy is the most prevalent indoor sensitization. It is associated with atopic dermatitis, perennial rhinitis and asthma. Chronic atopic dermatitis, which afflicts 2 % of people,1 results from reduced skin barrier function, often caused by mutation of
E¡ect of Long-term Use of Moisturizer on Skin Hydration, Barrier Function and Susceptibility to Irritants
, 1998
"... Moisturizers are often used in the prevention and treatment of irritant contact dermatitis. The present study was to deter-mine whether long-term daily use of a moisturizer on normal skin would a¡ect skin barrier function, hydration state, or susceptibility to sodium lauryl sulphate. Healthy volunte ..."
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Cited by 3 (0 self)
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Moisturizers are often used in the prevention and treatment of irritant contact dermatitis. The present study was to deter-mine whether long-term daily use of a moisturizer on normal skin would a¡ect skin barrier function, hydration state, or susceptibility to sodium lauryl sulphate. Healthy
Klf4 is a transcription factor required for establishing the barrier function of the skin.
- Nat. Genet.,
, 1999
"... Located at the interface between body and environment, the epidermis must protect the body against toxic agents and dehydration, and protect itself against physical and mechanical stresses 1-4 . Acquired just before birth and at the last stage of epidermal differentiation, the skin's proteinac ..."
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Cited by 118 (6 self)
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acquisition. Klf4 -/-mice die shortly after birth due to loss of skin barrier function, as measured by penetration of external dyes and rapid loss of body fluids. The defect was not corrected by grafting of Klf4 -/-skin onto nude mice. Loss of the barrier occurs without morphological and biochemical
Running title:Alcohol Ingestion and Skin Barrier
, 2006
"... D ow nloaded from 2Abstract Background: Topical ethanol is used as a dermal penetration enhancer in some commercial products. Previous studies have demonstrated that chronic ethanol consumption can also disrupt skin barrier function, leading to increased transdermal penetration. This observation bec ..."
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D ow nloaded from 2Abstract Background: Topical ethanol is used as a dermal penetration enhancer in some commercial products. Previous studies have demonstrated that chronic ethanol consumption can also disrupt skin barrier function, leading to increased transdermal penetration. This observation
Atom sharp microneedles, the missing link in microneedle drug delivery?
"... The skin barrier function is a major challenge for delivery of drugs via the skin. Located in the outermost layer of the skin, the stratum corneum (SC) consists of dead cells embedded in lipid regions, only 10–20 µm thick, tough but flexible and elastic. Hypodermic needles penetrate the skin succesf ..."
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The skin barrier function is a major challenge for delivery of drugs via the skin. Located in the outermost layer of the skin, the stratum corneum (SC) consists of dead cells embedded in lipid regions, only 10–20 µm thick, tough but flexible and elastic. Hypodermic needles penetrate the skin
Results 11 - 20
of
335