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Evolving Dynamical Neural Networks for Adaptive Behavior
- Adaptive Behavior
, 1992
"... We would like the behavior of the artificial agents that we construct to be as well-adapted to their environments as natural animals are to theirs. Unfortunately, designing controllers with these properties is a very difficult task. In this article, we demonstrate that continuous-time recurrent neur ..."
Abstract
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Cited by 308 (22 self)
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neural networks are a viable mechanism for adaptive agent control and that the genetic algorithm can be used to evolve effective neural controllers. A significant advantage of this approach is that one need specify only a measure of an agent’s overall performance rather than the precise motor output
Personality similarity in twins reared apart and together
- and Evolutionary Psychology – ISSN 1474-7049 – Volume 1. 2003. 94 One’s Twin: Perceived Social Closeness and Familiarity
, 1988
"... We administered the Multidimensional Personality Questionnaire (MPQ) to 217 monozygotic and 114 dizygotic reared-together adult twin pairs and 44 monozygotic and 27 dizygotic reared-apart adult twin pairs. A four-parameter biometric model (incorporating genetic, additive versus nonadditive, shared f ..."
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Cited by 118 (3 self)
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-environment component was small and negligible for all but 2 of the 14 personality measures. Evidence of significant nonadditive genetic effects, possibly emergenic (epistatic) in nature, was obtained for 3 of the measures. Until recently, almost all knowledge regarding environmental and genetic causal influences
The probability of duplicate gene preservation by subfunctionalization.
- Genetics
, 2000
"... ABSTRACT It has often been argued that gene-duplication events are most commonly followed by a mutational event that silences one member of the pair, while on rare occasions both members of the pair are preserved as one acquires a mutation with a beneficial function and the other retains the origin ..."
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Cited by 261 (2 self)
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incompatibility, i.e., speciation. The defunctions, is motivated by observations of tissue-specific patterns of expression of duplicate allozymes in tetrageneration of orthologues in different ways in two sister taxa effectively causes a divergence in genetic maps ploid lineages of fish The purpose
Linkage Learning via Probabilistic Modeling in the ECGA
, 1999
"... The goal of linkage learning, or building block identification, is the creation of a more effective genetic algorithm (GA). This paper explores the relationship between the linkage-learning problem and that of learning probability distributions over multi-variate spaces. Herein, it is argued that th ..."
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Cited by 232 (4 self)
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The goal of linkage learning, or building block identification, is the creation of a more effective genetic algorithm (GA). This paper explores the relationship between the linkage-learning problem and that of learning probability distributions over multi-variate spaces. Herein, it is argued
Non-additivity in protein-DNA binding
- Bioinformatics
, 2005
"... Motivation: Localizing protein binding sites within genomic DNA is of considerable importance, but remains difficult for protein families, such as transcription factors, which have loosely defined target sequences. In particular, it is generally assumed that protein affinity for DNA involves additiv ..."
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Cited by 29 (0 self)
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effects and exploit this information to improve binding site predictions using either weight matrices or support vector machines. The results underline the fact that, even in the presence of significant deformation, non-additive effects may involve only a limited number of dinucleotide steps
nonadditive genetic effects on survival in Chinook salmon
, 2005
"... The genes of the major histocompatibility complex (MHC) are found in all vertebrates and are an important component of individual fitness through their role in disease and pathogen resistance. These genes are among the most polymorphic in genomes and the mechanism that maintains the diversity has be ..."
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been actively debated with arguments for natural selection centering on either additive or nonadditive genetic effects. Here, we use a quantitative genetics breeding design to examine the genetic effects of MHC class IIB alleles on offspring survivorship in Chinook salmon ( Oncorhynchus tshawytscha
Generating Software Test Data by Evolution
- IEEE Transactions on Software Engineering
, 1997
"... This paper discusses the use of genetic algorithms (GAs) for automatic software test data generation. This research extends previous work on dynamic test data generation where the problem of test data generation is reduced to one of minimizing a function [Miller and Spooner, 1976, Korel, 1990]. In o ..."
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Cited by 183 (2 self)
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]. In our work, the function is minimized by using one of two genetic algorithms in place of the local minimization techniques used in earlier research. We describe the implementation of our GA-based system, and examine the effectiveness of this approach on a number of programs, one of which
Congruence of Additive and Non-Additive Effects on Gene Expression Estimated from Pedigree and SNP Data
"... There is increasing evidence that heritable variation in gene expression underlies genetic variation in susceptibility to disease. Therefore, a comprehensive understanding of the similarity between relatives for transcript variation is warranted— in particular, dissection of phenotypic variation int ..."
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Cited by 1 (0 self)
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into additive and non-additive genetic factors and shared environmental effects. We conducted a gene expression study in blood samples of 862 individuals from 312 nuclear families containing MZ or DZ twin pairs using both pedigree and genotype information. From a pedigree analysis we show that the vast majority
Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix
- Heredity (Edinb). 2005;95:221–227. 414 PTP4A1‐PHF3‐EYS and Alcohol Dependence July–August 2014
"... Correlated multiple testing is widely performed in genetic research, particularly in multilocus analyses of complex diseases. Failure to control appropriately for the effect of multiple testing will either result in a flood of false-positive claims or in true hits being overlooked. Cheverud proposed ..."
Abstract
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Cited by 171 (0 self)
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Correlated multiple testing is widely performed in genetic research, particularly in multilocus analyses of complex diseases. Failure to control appropriately for the effect of multiple testing will either result in a flood of false-positive claims or in true hits being overlooked. Cheverud
Nonadditivity in the effective interactions of binary charged colloidal suspensions
, 2009
"... Based on primitive model computer simulations with explicit microions, we calculate the effective interactions in a binary mixture of charged colloids with species A and B for different size and charge ratios. An optimal pairwise interaction is obtained by fitting the many-body effective forces. Thi ..."
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, then significantly negative and is then positive again. We finally show that an inclusion of nonadditivity within an optimal effective Yukawa model gives better predictions for the fluid pair structure than DLVO theory. (Some figures in this article are in colour only in the electronic version) 1.
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