Pfam is a comprehensive collection of protein domains and families, represented as multiple sequence alignments and as profile hidden Markov models. The current release of Pfam (22.0) contains 9318 protein families. Pfam is now based not only on the UniProtKB sequence database, but also on NCBI Gen

The OWL Web Ontology Language is a new formal language for representing ontologies in the Semantic Web. OWL has features from several families of representation languages, including primarily Description Logics and frames. OWL also shares many characteristics with RDF, the W3C base of the Semantic

of probability distributions — are best studied in the general setting. Working with exponential family representations, and exploiting the conjugate duality between the cumulant function and the entropy for exponential families, we develop general variational representations of the problems of computing

We examine the separation of ownership and control for 2,980 corporations in nine East Asian countries. In all countries, voting rights frequently exceed cash-#ow rights via pyramid structures and cross-holdings. The separation of ownership and control is most pronounced among family

To achieve high throughput rates today's computers perform several operations simultaneously. Not only are I/O operations performed concurrently with computing, but also, in multiprocessors, several computing

We generalize the method proposed by Gelman and Rubin (1992a) for monitoring the convergence of iterative simulations by comparing between and within variances of multiple chains, in order to obtain a family of tests for convergence. We review methods of inference from simulations in order

The use of hierarchy is an important component of object-oriented design. Hierarchy allows the use of type families, in which higher level supertypes capture the behavior that all of their subtypes have in common. For this methodology to be effective, it is necessary to have a clear understanding

Mirror Symmetry was discovered several years ago in string theory as a duality between families of 3-dimensional Calabi-Yau manifolds (more precisely, complex algebraic manifolds possessing holomorphic volume elements without zeroes). The name comes from the symmetry among Hodge numbers. For dual

The design and correctness of a communication facility for a distributed computer system are reported on. The facility provides support for fault-tolerant process groups in the form of a family of reliable multicast protocols that can be used in both local- and wide-area networks. These protocols

2 ’ + ’ and 2jcan be extracted by decomposing this signal on a wavelet orthonormal basis of L*(R”). In LL(R), a wavelet orthonormal basis is a family of functions ( @ w (2’ ~-n)),,,“jEZt, which is built by dilating and translating a unique function t+r (xl. This decomposition defines an orthogonal