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Receiver-driven Layered Multicast

by Steven McCanne, Van Jacobson, Martin Vetterli , 1996
"... State of the art, real-time, rate-adaptive, multimedia applications adjust their transmission rate to match the available network capacity. Unfortunately, this source-based rate-adaptation performs poorly in a heterogeneous multicast environment because there is no single target rate — the conflicti ..."
Abstract - Cited by 737 (22 self) - Add to MetaCart
as well as dynamic variations in network capacity (i.e., congestion). We describe the RLM protocol and evaluate its performance with a preliminary simulation study that characterizes user-perceived quality by assessing loss rates over multiple time scales. For the configurations we simulated, RLM results

Participation of Candida albicans Transcription Factor RLM1 in

by Cell Wall Biogenesis, A Delgado-silva, Catarina Vaz, Joana Carvalho-pereira, Catarina Carneiro, Ra Correia, Laura Carreto, Augusto Faustino, Rui Oliveira, Paula Sampaio
"... Candida albicans cell wall is important for growth and interaction with the environment. RLM1 is one of the putative transcription factors involved in the cell wall integrity pathway, which plays an important role in the maintenance of the cell wall integrity. In this work we investigated the involv ..."
Abstract - Cited by 1 (0 self) - Add to MetaCart
of RLM1 in the cell wall integrity. Additionally, the cell wall of C. albicans D/Drlm1 showed a significant increase in chitin (213%) and reduction in mannans (60%), in comparison with the wild-type, results that are consistent with cell wall remodelling. Microarray analysis in the absence of any stress

Inactivation of the Indigenous Methyltransferase RlmN in Staphylococcus aureus Increases Linezolid Resistance

by Jacqueline M. Lamarre, Benjamin P. Howden, Er S. Mankin , 2011
"... The indigenous methyltransferase RlmN modifies A2503 in 23S rRNA. A recently described rlmN mutation in a clinical Staphylococcus aureus isolate decreases susceptibility to linezolid and was thought to increase the extent of A2503 modification. However, we show that the mutation in fact abolishes Rl ..."
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RlmN activity, resulting in a lack of A2503 modification. Since many mutations could inactivate the rlmN gene, our findings unveil a potential mechanism for future linezolid resistance in clinical strains. The oxazolidinone antibiotic linezolid (LZD), introduced in 2000, is one of the newest

DOI 10.4171/RLM/669 Partial Di¤erential Equations — Existence and multiplicity results for anisotropic

by Stationary Schrödinger Equations, Ghasem A. Afrouzi, M. Mirzapour, Communicated On December
"... Abstract. — In this paper we are concerned with a new class of quasilinear elliptic equations with a power-like reaction term and a di¤erential operator that involves partial derivatives with di¤erent powers. The functional-analytic framework relies on anisotropic Sobolev spaces. By means of com-bin ..."
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-bined variational arguments, we obtain the existence of weak solutions and, in case of symmetric settings, the existence of large or small energy solutions. In particular, we establish some results that extend the classical theory of combined e¤ects of concave and convex nonlinearities.

The Saccharomyces cerevisiae MADS-Box transcription factor Rlm1 is a target for the Mpk1 mitogen-activated protein kinase pathway

by Evdokia Dodou, Richard Treisman , 1997
"... resistance to the toxic effects of constitutive activity of the Mpk1 mitogen-activated kinase (MAPK) pathway. The Rlm1 DNA-binding domain, which is similar to that of the metazoan MEF2 transcription factors, is also closely related to that of a second S. cerevisiae protein, Smp1 (second MEF2-like pr ..."
Abstract - Cited by 42 (0 self) - Add to MetaCart
upstream activation sequence activity. Tran-scriptional activation by Rlm1 requires its C-terminal sequences, and Gal4 fusion proteins containing Rlm1 C-terminal sequences also act asMPK1-dependent transcriptional activators. These results establish the Rlm1 C-terminal sequences as a target for the Mpk1

Methylation of 23S rRNA nucleotide G748 by RlmAII methyltransferase renders Streptococcus pneumoniae telithromycin susceptible

by Akiko Takaya, Yoshiharu Sato, Tatsuma Shoji, Tomoko Yamamoto - Antimicrob. Agents Chemother , 2013
"... Several posttranscriptional modifications of bacterial rRNAs are important in determining antibiotic resistance or sensitivity. In all Gram-positive bacteria, dimethylation of nucleotide A2058, located in domain V of 23S rRNA, by the dimethyltransferase Erm(B) results in low susceptibility and resis ..."
Abstract - Cited by 1 (1 self) - Add to MetaCart
and resistance to telithromycin (TEL). However, this is insufficient to produce high-level resistance to TEL in Streptococcus pneumoniae. Inactivation of the methyltransferase RlmAII, which methylates the N-1 position of nucleotide G748, located in hairpin 35 of domain II of 23S rRNA, results in increased

O’Brien: Verifying the strokefree phenotype by structured telephone interview. Stroke 2000, 31: 1076-1080 Meschia et al. -44- rlm (KN

by James F. Meschia, Robert D. Brown, Elizabeth J. Atkinson, Ms Peter - RD Brown Jr, I Meissner, LJ Hall, EJ Atkinson, PC
"... Background and Purpose—Case-control, cohort, and twin studies support a genetic contribution to ischemic stroke risk. Sibling pair linkage methods require identification of concordant or discordant siblings or both. We designed and tested a structured telephone interview to verify the stroke-free ph ..."
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as stroke free by interview if responses to all items on the questionnaire were negative. Results of the telephone interview were compared with data obtained from a systematic medical record review (benchmark). Results—Interview time was 5 minutes or less for all subjects. All subjects who began

Abstract Receiver-driven Layered Multicast

by Steven Mccanne, Martin Vetterli
"... State of the art, real-time, rate-adaptive, multimedia applications adjust their transmission rate to match the available network capacity. Unfortunately, this source-based rate-adaptation performs poorly in a heterogeneous multicast environment because there is no single target rate — the conflicti ..."
Abstract - Cited by 1 (0 self) - Add to MetaCart
as well as dynamic variations in network capacity (i.e., congestion). We describe the RLM protocol and evaluate its performance with a preliminary simulation study that characterizes user-perceived quality by assessing loss rates over multiple time scales. For the configurations we simulated, RLM results

Stability and Fairness Issues in Layered Multicast

by R. Gopalakrishnan, James Griffioen, Cormac J. Sreenan, et al.
"... Layered multicast is a promising technique for broadcasting adaptive-quality video to heterogeneous receivers. Past evaluation of layered multicast protocols has focused on the effectiveness of determining the maximal number of layers that can be delivered to each receiver. Unfortunately, this is on ..."
Abstract - Cited by 14 (3 self) - Add to MetaCart
us to question RLM’s ability to select the optimum number layers for a non-shared access link. We show that RLM is very conservative in its choice resulting in low link utilization.

Understanding the Management of Client Perceived Response Time

by David Olshefski, Jason Nieh - In Proceedings of the International Conference on Measurement and Modeling of Computer Systems (SIGMETRICS ’06 , 2006
"... Understanding and managing the response time of web services is of key importance as dependence on the World Wide Web continues to grow. We present Remote Latency-based Management (RLM), a novel server-side approach for managing pageview response times as perceived by remote clients, in real-time. R ..."
Abstract - Cited by 13 (1 self) - Add to MetaCart
of a web server complex, without any changes to existing web clients, servers, or applications. We have implemented RLM on an inexpensive, commodity, Linux-based PC and present experimental results that demonstrate its effectiveness in managing client perceived pageview response times on transactional
Results 1 - 10 of 49