A grand challenge in the post-genomic era is a complete computer representation of the cell and the organism, which will enable computational prediction of higher-level complexity of cellular processes and organism behavior from genomic information. Toward this end we have been developing a knowledge-based approach for network prediction, which is to predict, given a complete set of genes in the genome, the protein interaction networks that are responsible for various cellular processes. KEGG at

Abstract not found

], Facile [16], Obliq [7], Infospheres [11], the join calculus [13], and Nomadic Pict [33]. In this paper we address the issue of resource access control for such languages. Central to the paradigm of mobile computation are the notions of agent, resource and location. Agents are effective entities

General-purpose operating systems provide inadequate support for resource management in large-scale servers. Applications lack sufficient control over scheduling and management of machine resources, which makes it difficult to enforce priority policies, and to provide robust and controlled service

In addition to maintaining the GenBankÒ nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the data in GenBank and other biological data made available through NCBI’s Web site. NCBI resources include Entrez,

Interact hosting centers serve multiple service sites from a common hardware base. This paper presents the design and implementation of an architecture for resource management in a hosting center op-erating system, with an emphasis on energy as a driving resource management issue for large server

Grid technologies enable large-scale sharing of resources within formal or informal consortia of individuals and/or institutions: what are sometimes called virtual organizations. In these settings, the discovery, characterization, and monitoring of resources, services, and computations

This document is a revision of the public working draft dated 1998-08-19 incorporating suggestions received in review comments and further deliberations of the W3C RDF Model and Syntax Working Group. With the publication of this draft, the RDF Model and Syntax Specification enters "last call." The last call period will end on October 23, 1998. Comments on this specification may be sent to www-rdf-comments@w3.org. The archive of public comments is available at http://www.w3.org/Archives/Public/www-rdf-comments. Significant changes from the previous draft are highlighted in Appendix E. While we do not anticipate substantial changes, we still caution that further changes are possible. Therefore while we encourage active implementation to test this specification we also recommend that only software that can be easily field-upgraded be implemented to this specification at this time. This is a W3C Working Draft for review by W3C members and other interested parties. Publication as a working draft does not imply endorsement by the W3C membership. The RDF Model and Syntax Working Group will not allow early implementation to constrain their ability to make changes to this specification prior to final release. This is a draft document and may be updated, replaced or obsoleted by other documents at any time. It is inappropriate to cite W3C Working Drafts as other than "work in progress". This work is part of the W3C Metadata Activity.

Abstract not found

The rapid growth of the World-Wide Web poses unprecedented scaling challenges for general-purpose crawlers and search engines. In this paper we describe a new hypertext resource discovery system called a Focused Crawler. The goal of a focused crawler is to selectively seek out pages