in application codes written in Fortran, C, and C++. PETSc provides many of the mechanisms needed within parallel application codes, such as parallel matrix and vector assembly routines. The library is organized hierarchically, enabling users to employ the level of abstraction that is most appropriate for a

with the baculovirus insect cell expression system. After addition to cells, recFN matrix assembly was monitored by indirect immunofluorescence and by insolubility in the detergent deoxycho-

Abstract. Cells in culture reveal high levels of protein tyrosine phosphorylation in their focal adhesions, the regions where cells adhere to the underlying substratum. We have examined the tyrosine phosphorylation of proteins in response to plating cells on extracellular matrix substrata. Rat

n K . Assembling sample and image values in vectors, image reconstruction may be rewritten in matrix notation: With such linear mapping the propagation of noise from sample values into image values is conveniently described by noise matrices. The -th diagonal entry of the image noise matrix X

Cell phenotype is specified by environmental cues embedded in the architecture and composition of the extracellular matrix (ECM). Much has been learned about matrix organization and assembly through analyses of the ECM protein fibronectin (FN). FN matrix assembly is a cell-mediated process in which

The adhesion of cells to the extracellular matrix is a dynamic process, mediated by a series of cell-surface and matrix-associated molecules that interact with each other in a spatially and temporally regulated manner. These interactions play a major role in tissue formation, cellular migration

by repeatedly splitting clusters into smaller clusters. The splits are not based on any distance or similarity measure. The documents are assembled in to a matrix which is very sparse. It is this sparsity that permits the algorithm to be very efficient. The performance of the method is illustrated with a set

Abstract. The transition of cell–matrix adhesions from the initial punctate focal complexes into the mature elongated form, known as focal contacts, requires GTPase Rho activity. In particular, activation of myosin II–driven contractility by a Rho target known as Rho-associated kinase (ROCK

The Escherichia coli MG1655 genome has been completely sequenced. The annotated sequence, biochemical information, and other information were used to reconstruct the E. coli metabolic map. The stoichiometric coefficients for each metabolic enzyme in the E. coli metabolic map were assembled

Abstract. Interaction of cells with extracellular matrix via integrin adhesion receptors plays an important role in a wide range of cellular functions, for example cell growth, movement, and differentiation. Upon interaction with substrate, integrins cluster and associate with a variety